Treating a long standing plaque with subcutaneous b12/folate injections

[Bill]

Yes TL, a b12 (75mg per 100grams?) topical is available and there is published research on its use for psoriasis.

Thanks, Kat.

Thanks, Fred. I am thinking of it as something that might be done once or twice weekly in conjunction with an emollient, so more a booster for topical than a stand alone treatment, although with scalp, hands and feet, stand alone use would be less messy. Agree, the critical questions are "How much?" and "How often?".

Thanks, John. I am getting excellent control with DMF, so the vitamins probably have an easier task in my case.

Cheers

[Grizzly Bear]

Good to see the Psoriasis Club mad scientist continuing his work. 

Interesting trial Bill, it will be interesting to see how well it goes.

Personally I can't seeing it being the sort of treatment many would go for as having to inject each spot of psoriasis is going to take a long time, and you still don't know how much you need for each spot and how long it will last.  But that is just my opinion, and I do wish you well with it.

Fred.

Oi you, how dare you pick on our Bill !

Pick on someone your own size, you french tart you !

Bend over froggy

[Bill]

Another thought, TL. You may be able to get some liquid b12 and rub it into the plaques with some dimethyl sulphoxide.

Andy,

I have never found Fred as being anything other than kind, decent and fun. If ever you wish to experience a site run by a pack of sadistic, perverted bastards, then try Inspire.

Cheers

[Fred]

Andy,

I have never found Fred as being anything other than kind, decent and fun.

Cheers

Thank you for those kind words Bill. But don't worry about Grizzly, it's just a bit of banter that we often have together. Usually it's kept to the [Group Specific] board but he forgot his place and I will be putting him on toilet cleaning duties for the rest of the month. 

Back on track. How deep do you go ? I'm wondering if different depths may be worth monitoring.

[Bill]

I realise that, Fred.

The needle is 7mm, and I would inject at about 4-5mm depth, basically to a point where I don't meet resistance injecting. Bear in mind that skin thickness varies.

Cheers

[Fred]

I realise that, Fred.

The needle is 7mm, and I would inject at about 4-5mm depth, basically to a point where I don't meet resistance injecting. Bear in mind that skin thickness varies.

Cheers

Good point about the skin thickness. I will be watching this thread just like you other one, it's not for me but you have been here a long time and we all know that you are genuine and a respected member of Psoriasis Club.

[Bill]

An update. I continue with a daily subcutaneous injection of a bit over 0.15mls b12/folate (500µg/15mg per ml). The plaque became a bit red after applying sunscreen last weekend, but seems to have improved throughout the week, with the plaque less red and scaly, thinner, and starting to break up. I will continue with daily injections for now.

Cheers

[Fred]

As it's summer ? in your part of the world could that be helping too. Would be interesting to see a comparison on a part that wasn't getting sunlight.

Just a thought.

[jiml]

Looking very good Bill it certainly seems to be working very well

[Bill]

Good point, Fred. Here are a couple of pics of my elbow taken a few weeks apart (latest one just now) which show that it is getting better without any extra treatment. I have been taking 4*430mg of DMF a week for a few weeks, so that could be helping as well. The stuff behind my ears and the spot on my neck remain the same to my knowledge. I will have a better idea in a few weeks, but I do feel that the injections are helping.





Thanks, Jim.

Cheers