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Treating a long standing plaque with subcutaneous b12/folate injections

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Treating a long standing plaque with subcutaneous b12/folate injections
Bill Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
#1
Thu-05-12-2019, 10:31 AM
Time for another experiment. I have had a plaque on my right knee in some form for at least 25 years. I would treat it with topical and cover it in band aids, but I invariably develop an irritation to the band aid adhesive before the thing heals. After reading a bit of research relating to b vitamins and psoriasis, I thought I'd try a 5mg a day folic acid supplement along with a b complex supplement. This did bugger all, but a little more reading alerted me to a 1963 paper by some British researchers who claimed a 75% positive response (not sure what they mean) to subcutaneous b12 injections directly into plaques.

I don't have b12 for injections, but I do have injectable b12/folic acid (500micrograms/15mg per ml) and sterile insulin syringes suitable for subcutaneous injections. I have been injecting the plaque on my knee daily since Saturday (30/11/2019), initially with 0.075ml, and 0.15ml from Sunday. Below is an image I took of my knee at the start of treatment.

[Image: VNib8PD.jpg]

The response has been positive and quite rapid. I will post an updated pic tomorrow as I want to use natural light.

Cheers
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jiml Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 47,972
Threads: 357
Joined: Oct 2013
Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
#2
Thu-05-12-2019, 13:31 PM
Great experiment Bill it looks quite active in the before picture I look forward to seeing the next one as you think it's having a positive effect how long will you keep going with the treatment ? Will you stop when it's clear or do a periodic maintenance dose

I do like reading your experiments and admire the meticulous way you record everything
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Bill Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
#3
Thu-05-12-2019, 13:49 PM
Thanks, Jim, and I always appreciate your friendly manner and intelligent comment. Yes, it seems to be working. I will probably inject daily for another week or so, depending on how it goes, then perhaps twice weekly or less. I have also ordered a knee strap which will enable me to occlude the spot without using adhesive, so I might change to a combined treatment when that arrives. By the way, the vitamins I am using are for dogs and horses only. Woof!

Cheers
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Turnedlight Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 7,557
Threads: 67
Joined: Apr 2015
Gender: Female
Location: Uk
Treatment: Skyrizi
#4
Thu-05-12-2019, 19:03 PM
Very interesting - I look forward to hearing about the results. I imagine there’s quite a few treatments that drugs manufacturers would have very little interest in researching since they wouldn’t be able to monetise it. Take care and good luck Smile
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Bill Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
#5
Thu-05-12-2019, 20:04 PM
Thank you, TL. If it gets rid of the spot I will be pleased.

Cheers
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Bill Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
#6
Thu-05-12-2019, 21:16 PM
Here is what it looks like this morning.

Cheers

[Image: gePUnLA.jpg]
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Turnedlight Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 7,557
Threads: 67
Joined: Apr 2015
Gender: Female
Location: Uk
Treatment: Skyrizi
#7
Thu-05-12-2019, 21:50 PM
Wow that’s a visible difference already! Thumb
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Bill Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
#8
Thu-05-12-2019, 22:02 PM (This post was last modified: Thu-05-12-2019, 22:03 PM by Bill.)
Thanks, TL. So far, so good, but I cannot see injecting plaques with pet vitamins ever becoming a fad treatment. At least if it works I will have the last laugh.

Cheers
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jiml Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 47,972
Threads: 357
Joined: Oct 2013
Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
#9
Thu-05-12-2019, 22:17 PM
That's a big difference in a week Bill
I hope it continues working and you don't start barking
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Bill Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
#10
Thu-05-12-2019, 22:50 PM (This post was last modified: Thu-05-12-2019, 22:50 PM by Bill.)
I thinks it's pissing on trees in public that I should be worried about, Jim. Thumb
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