Posts: 10,094
Threads: 108
Joined: Dec 2014
Gender: Male
Location: Exmoor
Psoriasis Score: E = mc²
Psoriatic Arthritis Score: A = mc²
PQOLS: 69
Treatment: Carbolic Acid & Neat Bleach
Thu-13-07-2017, 17:04 PM
(This post was last modified: Thu-13-07-2017, 17:05 PM by Grizzly Bear.)
(Thu-13-07-2017, 14:42 PM)Caroline Wrote: [To see links please register here]
(Thu-13-07-2017, 14:37 PM)Caroline Wrote: [To see links please register here]
(Thu-13-07-2017, 14:28 PM)Maryam Wrote: [To see links please register here]
(Thu-13-07-2017, 14:23 PM)Grizzly Bear Wrote: [To see links please register here]
I'm afraid i can't help you, sorry Maryam 
I do know what an IL-76 is though 
I actually had to google that 
My guess: it is a train....
Nooooo 
it is an aircraft...
I thought that where Bill is our mad scientist, GB is our mad train driver, so it had to be a train...
I beg your pardon
Our Bill is not a mad scientist
I am not a mad train driver
Maryam was mentioning IL- with numbers, I mentioned that I could not help with that but I knew what an IL-76 was !
Now, poor Maryam thinks I'm daft
And she'd be right
Poor Maryam
Posts: 260
Threads: 9
Joined: Jun 2017
Gender: Female
Location: The Netherlands
Psoriasis Score: 0!!!
Treatment: Stelara
Posts: 10,094
Threads: 108
Joined: Dec 2014
Gender: Male
Location: Exmoor
Psoriasis Score: E = mc²
Psoriatic Arthritis Score: A = mc²
PQOLS: 69
Treatment: Carbolic Acid & Neat Bleach
(Thu-13-07-2017, 20:20 PM)Maryam Wrote: [To see links please register here]
Oi, why are you laughing young lady ?
I'm not really daft Maryam..........honest
OK, just a little bit then, OK
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
Mad scientist? Lucky lab rat more like. DMF action? NRF2 activation; HO 1 induction via GSH depletion; apoptosis of mature T and dendritic cells (i.e. memory cells) and activation of NK cells, resulting in a shift to an anti-inflammatory response; Increased mitochondrial function. The mechanism of action is complex and the pharmacological effect is not identical for individuals. It is a good basis for thinking about the drug, but you can only learn by trial and error.
Posts: 28,487
Threads: 117
Joined: Nov 2011
Gender: Female
Location: In between the tulips
Psoriasis Score: 3
Psoriatic Arthritis Score: 3
PQOLS: 4
Treatment: Got back to DMF slow release
You know that "mad scientest" Is our pet name for you over here at psoriasisclub.
It is kind of a signal of respect for every very special research that you are doing. But if you like that we call you a "Lucky lab rat"
, that is also fine with me.
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
No offence taken, Caroline. Experimentation is the sole reason that DMF continues to be a safe and effective treatment for me.
Cheers
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