Tremfya for psoriatic arthritis Fred's journey

[D Foster]

If it's IL17&23 are they are another version of Stelara.

No Stelara is a mix of IL12 and IL23 Dave.

It's worth trying one that targets the same as stelara as they may well target to inhibit those ILs in a different way

There isn't one that targets both 12 and 23.

Tremfya which I'm on now targets IL23

Sorry Fred yes IL12 but I am sure that I read that the combination of IL12&23 had an effect on IL 17.

[Fred]

If it's IL17&23 are they are another version of Stelara.

No Stelara is a mix of IL12 and IL23 Dave.

It's worth trying one that targets the same as stelara as they may well target to inhibit those ILs in a different way

There isn't one that targets both 12 and 23.

Tremfya which I'm on now targets IL23

Sorry Fred yes IL12 but I am sure that I read that the combination of IL12&23 had an effect on IL 17.

Could be Dave, but I can't go back to Stelara even if I wanted too.

[Fred]

For reference 12 Sep 21: Psoriatic arthritis score has gone up from 1 to 9 in a week. Also been feeling very tired and ankle is swollen up again.

[jiml]

For reference 12 Sep 21: Psoriatic arthritis score has gone up from 1 to 9 in a week. Also been feeling very tired and ankle is swollen up again.

Your numbers are fluctuating wildly Fred no apparent reason . Hopefully the dermatologist may have some suggestions to get things stable again, won't be long now to find out

[Fred]

For reference 12 Sep 21: Psoriatic arthritis score has gone up from 1 to 9 in a week. Also been feeling very tired and ankle is swollen up again.

Your numbers are fluctuating wildly Fred  no apparent reason . Hopefully the dermatologist may have some suggestions to get things stable again, won't be long now to find out

Yes Jim it's getting a bit annoying. A few weeks ago I felt great and took my next shot, now I wish I hadn't.

Appointment Monday week so yes not long to go.

[D Foster]

It looks like something to do with the covid third vaccine shot , I will be very interested in what they say about that as we may be getting ours soon and I am wondering whether to take it.

[Fred]

It looks like something to do with the covid third vaccine shot , I will be very interested in what they say about that as we may be getting ours soon and I am wondering whether to take it.

I don't think it's the covid jab this time Dave as I had my third one 8 weeks ago now and the psoriatic arthritis had almost gone 3 weeks ago.

[D Foster]

It looks like something to do with the covid third vaccine shot , I will be very interested in what they say about that as we may be getting ours soon and I am wondering whether to take it.

I don't think it's the covid jab this time Dave as I had my third one 8 weeks ago now and the psoriatic arthritis had almost gone 3 weeks ago.

That's encouraging, I don't know whether to take the third shot when it's offered Fred.

[Fred]

It looks like something to do with the covid third vaccine shot , I will be very interested in what they say about that as we may be getting ours soon and I am wondering whether to take it.

I don't think it's the covid jab this time Dave as I had my third one 8 weeks ago now and the psoriatic arthritis had almost gone 3 weeks ago.

That's encouraging, I don't know whether to take the third shot when it's offered Fred.

Only you can decide that Dave. I can have a fourth shot now if I want, but I'm waiting till I see my dermatologist first to get her view on it.

[Bill]

That is frustrating. Is it an allergic reaction? The stuff works then it doesn't? "Better the devil you know." they say, but I would be looking for another devil.