Hi Folks I'm Back ! having been taken off the Ixekizumab trial and my skin has returned to NORMAL moderate to severe scaling I have now been prescribed FUMADERM, started Mon 12/09 2016. To begin I am on one (Fumaderm Initial) 30mg tab per day for the first week increasing each week by +1 30mg tab for four weeks then moving on to full dose 120mg and increasing weekly until I reach the max dose which I think is x 2 120mg 3 times a day then reducing the dose untilI find the lowest dose that keeps my skin clear. having been clear for over 6 months while on the Ixekizumab I am taking bad with having to deal with full blown psoriasis and am Hoping this will finally be my fix.

Has anyone tried the diet where you do not eat Nightshade family of food to elliminate psoriasis?
I have heard that this has worked for many. I would really appreciate if anyone has experience of this.

Does any one have any opinion on smoking tobacco and what if any side effects it may have on plaque psoriasis. 

I have read it can be a problem.   

what is your take on it?

Hi
I am a 46y/o guy I have had psoriasis most of my life.  In more recent years I have been diagnosed with psoriatic arthritis as well.  I have moved from several messy creams, light treatment, pills, and Enbrel, Stelara, and Humira injections.  Most recently I have had an acute reaction to Humira after moving from bi-weekly injections to weekly injections.  The reaction started as an itchy rash on both arms and quick spread up my arms over my shoulders and into my trunk area.  My dermatologist has just taken me off Humira completely.  At this point I am waiting for the Humira to clear my system so I can start cosentyx in about a month.  I am hoping for better results with cosentyx.

It's a couple of months since I decided to stop any treatment (yes even natural ones) and I'm patchier than ever, but I've been wandering about with vest tops on and honestly forgetting what I look like- I may have had funny looks but I haven't noticed them.

It itches a bit but not that much especially if I do moisturise (which I don't bother with that much) but I feel free - and no longer being coerced into taking nasty drugs just in an attempt to look nice for others.

If my psoriasis goes nuts again, then I will look at taking something, I have had uncontrollable itching in the past so I don't take it lightly, but for now it's just cosmetic and I'm just leaving it alone.

So, has anyone else decided to just give up on treatment and bare all? I think it would be great if we actually see more psoriasis in daily life, and maybe people will just get used to it instead of wondering if we have plague or something!

Hi all,

I'm Paul from North Wales and I've had Plaque Psoriasis for just over 30 years. I don't get "attacks", it's just always there, and I've tried most lotions and potions over the years (with the exception of immunosuppressants - my general health has been good so I've always put that ahead of improving my skin) but not had a lot of success. I was under a dermatologist for a while but these days I just pop to see my GP if I need more Capasal shampoo - which I use as a shower gel as well as for my hair.

Every 5 years or so I look to see if there is anything new on the market and give it a go. This time it was my wife that found out about Enstilar and my GP put me on it 4 weeks ago. The results so far have been good, the flaking stopped within days and I think the redness is slowly improving.

I'm curious to know anyone elses experiance with Enstilar, and in particular what they did after the 4 weeks initial treatment had finished. And, of course, if I can be of any help to anyone else with advice about the condition in general, I'd be happy to give my view.

All the best,

Paul

Hi all, 

I have been taking snippets of advice from your site for a good while now and finally got around to joining up.

I have been prescribed Acetretin and if anything my condition seems to be worsening and i wondered if anyone else had experienced this.

My lepery history in brief......
My condition started around 1995 when I was 24 with scalp psoriasis, I have large coverage on both my upper and lower legs, elbows, arms back, scalp, ears, basically all over.

In the last 12 months my condition has worsened and often gets me really down, I am sure you all appreciate the time when summer finally arrives and everyone is in shorts, but you cant wear them or go swimming because your condition looks so unsightly. I could really start moaning, but that wont get me anywhere!

Up until recently I have been using Dovabet ointment and I have tried courses of UVB treatment. The UVB was moderately successful, but it took up so much of time I bought my own UVB machine for home with the same lamps etc, ensuring I recorded my usage and didn't over do it. 

I started a course of Acetretin back in July and my back has never been worse, I have a new outbreak on my shoulders and this weekend an outbreak on my chest, I have been to the clinic this morning to see the nurse, who has booked me another appointment and suggested im considered for a course of Methotrexate or Ciclosporin, Im concerned that I cannot consume any alcohol while using Methotrexate, (I'm no heavy drinker, but do enjoy a few beers with my friends and a bottle of wine or so with my wife).

I could waffle on for hours, but I guess my real question is has anyone had any similar experiences to me and can they offer me any advice.

Finally, I have private health (Bupa) has anyone gone down this route and is the treatment any better / quicker?

Thanks in advance

Hi There,

I've just joined this site as I've been on methotrexate for 6 weeks and am feeling so tired and sad. I've been told to stay on the pills for at least 4 months to see results. Some people say that the side affects fade away after a while - is this true? I am in New Zealand with psoriasis on elbows, knees, hand and toe. Just feeling a bit despondent. Hopefully things will get better

How on earth do you do html scrolling text codes? I tried one earlier, but it wasnt picking it up

Hello, my name is Madeline, I have been diagnosed with pustular psoriasis since April this year. I have it in one area on the heal of my foot.
 I have been prescribed Clobovate and cloboderm since then with no affect.
 Today after visiting a dermatologist he has advised clobovate-exorex-dovonex in a monthly rotation also using doing film or similar. Please keep fingers crossed as at present it it very sore to walk.

hello my friends. does anyone on acetretin have probs with their immune system I seem to be picking up infections quite often n its getting me down. Linda

I know that the leaflet prescribed with betnovate and dovobet says it shouldn't be used on the face and doctors/dermatologists advise the same but I have the smallest red circle on the very end of my nose that only responds to betnovate or dovobet. I was given another cream to use on my face if I needed to but this cream does absolutely nothing. 

I recall someone on here mentioning in another topic that they have used dovobet on their face without problems and that is stronger than betnovate right? Do you think it would be a problem to apply a little bit of betnovate daily? Or even every other day? If I stop using betnovate for a couple of days the spot returns.

Again, the area on my nose is tiny, I don't even have to rub the cream in to cover the area. It's about the size of one of the dots on a small dice.

Hey all! I'm a 29 year old male that has had psoriasis since I was about 13. I have been on Raptiva when I was 18 (and it worked great, until it was pulled from the market), Otezla (It did not work on my P or my PsA), Humira (Worked wonders on my PsA, but did absolutely nothing for my P), and I just took my first loading dose of Cosentyx last week. I am hoping it works, as I'm tired of using topical steroids. Glad I found a forum with others with this awful, awful condition. Just wanted to say hi!

I've just signed up today as I feel I need to share this with all fellow sufferers. I've suffered for years, nails, feet, elbow, knees, bottom. I've used every potion known to no avail.  however I recently suffered extremely bad back pain and have had steriod in junctions to my facet joints...i am 2 weeks post injections and I do not have one patch on my body....true, honestly, have any doctors on this forum a reason behind this and why is it not being offered as a solution to the terrible creams and medication? ...  Has anyone else had the same injections with the same results?

Hello there fellow sufferers,
Thankyou very much for accepting me to this forum and I hope you can help me with some questions that I have regarding my current medication. 
I've suffered with guttate psoriasis for almost 20 years now but until the last couple of years it's been kept fairly under control with various emollients and topical steroid cream/ointments. It became much more severe and more widespread following my hysterectomy 2 years ago, though this could just be a coincidence, my consultant thinks it could be but is a bit noncommittal. In the past 9 months, I've had two courses of light therapy, the last one ending at the beginning of July, within a week, my psoriasis started appearing again so I immediately contacted dermatology, saw the consultant and was put on Acetretin 25mg daily. 
I've been taking it for almost 4 weeks now and disappointingly my condition seems so much worse, with terrible itching, burning and flaking skin, EVERYWHERE!! 
I hoped I might see an improvement by now, my consultant said I should. I was just wondering if anyone else could provide me with any advice or their experiences with this  drug.
I wait with eager anticipation.

Many thanks
Mandy x

Hello, I have had psoriasis for 26 years and had all the usual topical treatments , had 5 treatments of UVB and 1 of uva but took puva pain. Neotigison didn't work and methotrexate caused me liver problems. Now on Stelara and I am very hopeful it works. Had first injection on Friday and don't know if it's my imagination but my skin feels different. Happy to hear any other experiences

Recently diagnosed with psoriasis of buttocks. had seen family physician for rash and he diagnosed it as a fungal infection. After treating it for two week with very expensive anti fungal cream with no results, made an appointment with dermatologist. He diagnosed it as psoriasis and prescribed a steroidal cream which I could only use for two weeks. it was better but not gone. he then prescribed an antibiotic pill which I took for 10 days. That also helped but it didn't go away. I had about two weeks of releif and it came back. Now I am trying saturating it with apple cider vinegar using cotton balls and taking one tablespoon of apple cider vinegar with honey in a cup of hot water. Too soon to tell if this is going to work.

Hi very new to this. I have had psoriasis for 42 years and I'm having the worst flare up I've ever suffered all because of a viral sore throat and I'm 90% covered in guttate psoriasis feeling miserable to be fair

Been perscribed Dovobet by my dermatologist for my psoriasis. It has worked well on some patches but not so much on the biggest and most stubborn patch that I have on the side of my lower leg. Seems to have removed much of the background redness but there are like 4-5 small spots on a pinkish background. The spots are quite sensitive to touch like when you get a pimple.

I was perscribed the dovobet scalp application which my dermatologist and the leaflet says is fine to use on psoriasis elsewhere on the skin. Just wondering if it's worth getting it in ointment form or whether results will be exactly the same?

Finally, would it be worth looking in to trying Dovonex? I've seen the Dovonex V Dovobet comparison thread but was just wondering whether any one has had any experience with Dovobet not working too well but Dovonex improving their psoriasis?

Thank you.

Another newbie on the horizon for psoriatic arthritis. More study needed, but the future is looking towards these types of treatments.

Quote:

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Objective:
To evaluate the efficacy of clazakizumab, a monoclonal antibody with high affinity and specificity for the interleukin-6 (IL-6) cytokine, in psoriatic arthritis (PsA).

Methods:
In this randomized, double-blind, placebo-controlled, dose-ranging study (ClinicalTrials. gov identifier: NCT01490450), patients with active PsA and an inadequate response to nonsteroidal antiinflammatory drugs were randomized (1:1:1:1) to receive subcutaneous placebo or clazakizumab 25 mg, 100 mg, or 200 mg every 4 weeks, with or without methotrexate. The primary end point was the response rate according to the American College of Rheumatology 20% criteria for improvement (ACR20) at week 16, with secondary efficacy end points at weeks 16 and 24.

Results:
A total of 165 patients were randomized. At week 16, the ACR20 response rate was significantly higher with clazakizumab 100 mg versus placebo (52.4% versus 29.3%; P = 0.039). ACR20 response rates at week 16 were 46.3% with clazakizumab 25 mg (P = 0.101 versus placebo) and 39.0% with clazakizumab 200 mg (P = 0.178 versus placebo). ACR50/ACR70 response rates were numerically higher with clazakizumab versus placebo at weeks 16 and 24. Compared with placebo, clazakizumab treatment significantly improved musculoskeletal manifestations (joint signs and symptoms, enthesitis, and dactylitis), with minimal improvements in skin disease, without clear evidence of a dose response. Clazakizumab was well tolerated.

Conclusion:
This is the first clinical trial of an IL-6–targeted therapy in PsA. Clazakizumab may be an effective treatment option for musculoskeletal aspects of PsA, but because of the lack of a dose response in this study, further studies are required to confirm the appropriate dose. The safety profile is consistent with the pharmacology of IL-6 blockade and prior clinical experience with this antibody in rheumatoid arthritis.