For a couple of years I have been switching between dovobet and silkis (calcitriol) for my skin but after returning from my adventure Stateside I had to get a new prescription (my luggage went on an adventure of it's own - with all my creams/ointments in it) and was surprised to discover that my pharmacist had given me dovobet gel....

I had no idea there was a gel.... It comes in a really handy bottle that enables you to apply small drops to the affected area, and it is so much less greasy than the ointment I had been using before.

So far I have found it appears to be more effective in clearing my skin, perhaps because it is more readily absorbed into the skin.

Has anyone else used it? If so, what are your opinions?

Krissie

Hi everyone and good afternoon evening wherever you are!

Went to the doctors last week and asked for exorex lotion as I had heard it was very good for clearing up guttate psoriasis! It has cleared across my chest nearly gone from arms, legs are starting to look more sunburnt now, which is how my chest looked before it eventually went away! tummy is looking much better too and more sunburnt also.

Has anyone used the lotion? I quite like it although it can't be used if you are planning on going out into the sunshine because it contains real coal tar! It smells okay too and is quite a thin lotion and pleasant to use.

anyone else had good results using exorex. It is really expensive too if you can't get it on prescription.

Thank you all

Have a great afternoon evening

xx

Novartis announced today top-line results from the head-to-head Phase III psoriasis study which showed the superiority of secukinumab (AIN457) in clearing skin to Enbrel®* (etanercept), an anti-tumor necrosis factor (anti-TNF) therapy. In addition, secukinumab (AIN457) met all primary and secondary endpoints.

The FIXTURE trial (the Full year Investigative eXamination of secukinumab vs. eTanercept Using 2 dosing Regimens to determine Efficacy in psoriasis) was a randomized, double-blind, double-dummy, placebo-controlled, multicenter global study of subcutaneous secukinumab (AIN457) in moderate-to-severe plaque psoriasis involving 1,307 patients. It was designed to demonstrate efficacy after 12 weeks of treatment, compared to placebo and etanercept, and to assess the safety, tolerability and long-term efficacy up to 52 weeks. Established treatment measures were used to assess the efficacy of secukinumab (AIN457) including PASI 75 (Psoriasis Area and Severity Index 75) and the Investigator's Global Assessment (IGA mod 2011), a standard tool to assess the clearing of skin after treatment.

"These results showing that secukinumab (AIN457) is superior to Enbrel, a current standard-of-care therapy, are great news for people living with moderate-to-severe plaque psoriasis," said Tim Wright, Global Head of Development, Novartis Pharmaceuticals. "With 40-50% of people living with moderate-to-severe plaque psoriasis dissatisfied with their current therapies, there is clearly an unmet medical need for new therapies that act faster and longer to relieve pain, itching and other symptoms."

Full results from the secukinumab (AIN457) Phase III study program, the largest undertaken in moderate-to-severe plaque psoriasis to date, are expected to be presented at major medical congresses later this year.

Secukinumab (AIN457) is the first medicine selectively targeting IL-17A to present Phase III results. IL-17A is a central cytokine (messenger protein) in the development of psoriasis, and is found in high concentration in skin affected by the disease. Research shows that IL-17A plays a role in driving the body's autoimmune response in disorders such as moderate-to-severe plaque psoriasis and is a preferred target for investigational therapies.

In the FIXTURE study, the observed safety profile of secukinumab (AIN457) was consistent with previously reported results from Phase II studies in moderate-to-severe plaque psoriasis and no new safety concerns were identified.

Source: NO LINKS ALLOWED

Hi I was just wondering how people cope with constant itchiness. I have had Psoriasis for 35 years on and off. But after having a clear spell of about 4 years. It has come back with avengance and I am struggling to cope with the itchiness all the time and i'm being really good putting on my creams but to no relief.

Hello
Im very new to this site so just wanted to post something.
I, also have guttat psoriasis and this is my first time actually talking/chatting/posting to anyone that have the same condition

Good evening all,
Having recently been diagnosed with Psoriasis at the age of 63 it came as quite a shock, never having had a skin complaint in my life before.
I am slowly coming to terms with it and hope to have it under control soon. Finges crossed.
No doubt there is a lot to learn about this problem hence my reason or joining this forum.
Hopefully lots of answers to my questions will be on the site somewhere once I have found my way around.
Thanks for reading my post and it won't be the last you hear from me.
Regards, Ed's Mom

Hi everyone and good morning

Has anyone used glycerin on their skin to treat their psoriasis? What is the best way to use it? Do you apply directly to your skin or mix it with lotion or something? Is it effective. I have guttate which is fading in some areas but have heard great things a bout glycerin.

Amazon seem to have a huge range of glycerin to buy, which one is the best?

Thank you

Hope you all have a nice day!

xx

I have 1 Humira pen leftover, unused, unopened, kept refrigerated that I do not need anymore. I hate to throw it away. Any ideas what to do with it? Is it legal to sell it??

I was on Humira for 2 years, but it stopped working for my Psoriatic Arthritis. I am now on Remicade.

Thanks for any input!

Hello I always take alcohol or brandy for about 4 to 5 shots just to make me sleep every night. My question is its really worse my Psoriasis problem?

Hi all,

Just joined this forum, found it while browsing psoriasis, (can just about spell it now) and treatments.
I'm 48 and have had this condition for around 10 years now, it started in my scalp but spreads to different bits of me and in different forms - whenerver and wherever it pleases.
At the moment I've got the scalp flaky patches in my scalp (they are a constant). Elsewhere there are some red blotches and large reddish spots in other places.
I don't get how it changes though - other times I've had scaly and flaky blotches but not now, instead they are red and sore.
I use T Gel on my scalp - I heard olive oil was good, has anyone tried this, also that you should wash your hair and scalp in cool water, not hot??
I've used creams but don't remember what they were - once used a steroid cream, which seemed to make it worse so I stopped. Anyone any tips for complementary medicine?

Cheers folks,

Filmbuff

Hello how is everyone tonight? Me, I am just blah. I am tired of my Psoriasis, just like everyone else on this forum probably is. I am new to this forum, so here is a bit about myself:

I am 33 and had Plaque and Inverse Psoriasis since I was a kid and was official diagnosed in 2003. Also, I have had pain in my hip and hands/fingers since I was a kid. I have not been diagnosed with PsA or RA as of yet. For my P, I have tried the following laundry list of medications: Cellcept, Enbrel, Methotrexate, Humira, Soriatane, and now Stelara and Celebrex.

Stelara has been the best so far; I am approximately 85% clearance without any visible inflammation after three shots. However, my hips and hands/fingers still hurt considerably. My Dermatologist thinks I could have PsA, and recommended that I see a Rheumatologist. My new Rheumatologist mentioned the M word (methotrexate; a curse word to me) 31 times during the visit. I had some blood work done (no results yet), and eight x-rays.

For the most part, I can live with the pain in my hip and hand/finders, but now I have stiffness and fatigue every morning (feels like I beat myself up in the gym for the first time in a long time). The stiffness and fatigue came directly after I stopped Humira (Humira cause my P to flare). I am sorry for the wall of text. I am a HTFU type of guy, but for the first time in my life I just want to cry. I hate this curse! I am thinking about giving up Stelara, but is there anything else left? Any suggestions?

I was just prescribed urea lotion a few days ago. An addition to my regimen. There's no limit in using it. We can use it twice a day or as needed. It attracts water hence it moisturizes the affected areas. It helps me specialLy on my elbows. Psoriasis in these areas became thinner after 3 days of using the lotion..

Hello everyone!

Just been looking on amazon at pine tar soap. Has anyone ever tried it for psoriasis? Is it any good? and is it safe? I have heard it may contain creosote which causes cancer

If anyone has tried it what did you think?

Hope your all having a nice day!

xx

Hi!  I came from the Philippines.  I have psoriasis for over 6 years, just an estimate[/font].  I just could not remember when it started.  I was diagnosed sometime in 2010.  However, i did not mind it too much as it only started on my left elbow. Though I didn't mind it too much, I had gone from one doctor to another.  I was prescribed ointments for anti-fungal infections however it was not cured.  Then early this year, i noticed a red spot below my throat which prompted me to see a dermatologist.  That was on February 5, 2013 that I started seeing a derma. You know what the derma told me?  She said i'm lucky my psoriasis has not spread all over my body.  Now, i have them in both hands, and some parts of my body.  Thanks to the dermatologists that i visited my psor is controlled.  Actually i visited 2 dermas one in the place where i live and the other is in Quezon City.  Both of them are so good.  I love seeing them both.

Hi everyone!

Haven't posted in a couple of weeks as I am still finding my way around the site.

My doctor has prescribed Daktacort cream for me 1%. It seems really good and has cleared up a couple of inverse patches of psorasis for me.

As I mostly have guttate and it seems much dryer I am wondering if it will now get better on its own or can I use some of the daktacort, little bits at a time on small patches of skin to treat some of the guttate.

As i said on a previous thread I wouldn't use the cream all over as it is cortisone and not good for all over use as it is bad for the adrenal glands and also thinning of skin.

I have had guttate now for nearly a month and am fed up of it and want it to clear which i am hopeful it will do in time. But i would like to clear it up quicker if i can.

Thank you for listening

xx

Well, I went for my follow up appointment today, and was put onto Acitretin (Neotigason).
I have been put on a daily dose of 30mg, and I have to go for blood tests in 3 weeks, ready for my next appointment in 4 weeks.
I have taken my first dose today and will monitor my progress for the next few months to see what sort of progress I achieve.
Will keep you updated as I go.

Let's see how this works eh !!!!

So you've often heard and probably wondered is it true that alcohol is bad for psoriatic arthritis! Personally I have never noticed any difference, and when I was in hospital for a week they gave me Red Wine with my dinner.

This is a study from researchers at the Leiden University Medical Centre in The Netherlands. Make your own mind up Cheers.

Quote:

---

Objectives:
There are conflicting reports concerning the association between alcohol consumption and RA. We performed a case–control study to investigate the association of alcohol consumption with RA as well as with other forms of arthritis. To assess whether alcohol consumption affects long-term disease outcome, we also investigated its association with radiographic progression and sustained drug-free remission in RA.

Methods:
Patients with arthritis and various diagnoses including RA, OA, ReA, SpA and Psoriatic Arthritis (PsA) were compared with 5868 controls from the general population. The association of disease with alcohol consumption was analysed by logistic regression analysis.

Results:
Alcohol consumption was inversely associated with not only RA [odds ratio (OR) 0.28, 95% CI 0.23, 0.35] but also OA (OR 0.31, 95% CI 0.16, 0.62) and other forms of arthritis (OR 0.34, 95% CI 0.24, 0.48). A higher degree of systemic inflammation, reflected by the ESR and CRP level, was associated with a smaller proportion of patients consuming alcohol. There was no dose–response relationship between the amount of alcohol consumed and the presence of arthritis. The extent of joint destruction and the rate of sustained drug-free remission were not affected by alcohol consumption.

Conclusion:
Arthritis patients report less alcohol consumption than controls, regardless of the type of arthritis. This suggests that alcohol may either protect against different kinds of arthritis or that the inverse association between alcohol and arthritis may be secondary to disease development, with arthritis patients being less inclined to consume alcohol due to their decreased general well-being.

Hello I'm 45 year old living with Psoriasis and as of now i don't take any medications. It starts two years ago, now its already spreading on my whole body.

Below is translated with Google Translate and checked on correctness.
It shows a recent investigation in the Netherlands in which it is clear that MTX is useless when trying to beat PsA. But that doctors keep on prescribing.
The article can be read (in Dutch) at LINK REMOVED

MTX senseless with Arthritis Psoriasis
A double-blind randomized studies has shown no evidence that six months of treatment with methotrexate (MTX) is effective against synovitis in psoriatic arthritis (PsA). The researchers wonder whether MTX in PsA is effectively a DMARD.

The doctor who prescribes MTX in PsA, does something what many of his colleagues do too. He is even encouraged to do so by the guidelines, while the effectiveness of this treatment has not been conclusively proven. Nevertheless the NICE guidelines advise to try MTX  before considering - well proven effective in PsA - TNF-alpha inhibitors.

British researchers therefore decided to put to test, which was not done before, the effect of MTX in PsA a randomized clinical trial (Rheumatology. 2012, 51 (8) :1368-77). The 221 participants had active PsA and were randomized to 15 mg MTX weekly or placebo. The primary outcome were the Psoriatic Arthritis Response Criteria (PsARC). Secondary outcome measures were the scores of ACR20 and DAS-28, and the seperate items in them.

44 participants, about equally divided between the two groups could not be involved in the follow-up, 26 participants discontinued treatment (14 in the MTX group). After six months no significant effect on PsARC (OR 1.77), nor on the ACR20 or DAS28 score (OR 2.00 respectively. 1,70) showed. Nor has there been significant positive effects of MTX on the number of tender and swollen joints, erythrocyte sedimentation rate (ERS), C-reactive protein (CRP), evaluation of health (HAQ score) and pain perception.

Although there was a trend towards improvement in MTX use, but none of the indices referred to this effect reached statistical significance. The only positive effects of MTX were an improvement of both the doctor and patient global scores and skin scores. The safety was as expected.

The authors conclude that the results do not indicate any improvement of synovitis in PsA by treatment with MTX. They recommended to practitionars that patients should be used with effective conventional means as leflunomide and biologicals.

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Additonal remarks from me... Biologicals can be very dangerous as part of the immune system is inhibited.

Instead, it is found that psorinovo (DMF) used with psoriatic arthritis (PsA) in 9 of the 10 cases gives disappearance and brings much less risk, if the recommended dose is not exceeded. This is demonstrated by including research in 2008 of dr. L. Kunst.

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Name            Type          dose                                      price/year
Remicade      infliximab    5 mg/kg 1 x per 2 months      € 19.352.-
Humira          adalimumab  1 x per week 40 mg                € 32.480.-
Enbrel            etanercept    2 x per week 50 mg              € 28.260.-
Psorinovo      DMF            6 x day 120 mg                      € 1.200,-

Fred im not getting an email for new threds in help me or intros