Otezla and rash

[Duncan]

Had to come off it in the end. Going to the toilet 7 or 8 times a day. It got worse not better.
My skin was starting to look good. Even my joints felt better than ever.
I even ended up with slight swelling in my lower legs. Just had to come off it. I gave it 1 hell of a go but went through hell and back. I really wanted them to work.
Back to Hospital this week. Limited to oral as I have high blood pressure and drink

[jiml]

Had to come off it in the end. Going to the toilet 7 or 8 times a day. It got worse not better.
My skin was starting to look good. Even my joints felt better than ever.
I even ended up with slight swelling in my lower legs. Just had to come off it. I gave it 1 hell of a go but went through hell and back. I really wanted them to work.
Back to Hospital this week. Limited to oral as I have high blood pressure and drink

Hi Duncan I agree you gave it a good try and the sad thing is that it worked but caused so many other problems
Can I suggest when seeing the dermatologist this week that you ask about skilarence it's the same drug that I'm on but licenced and approved for use here in the UK I find it keeps the plaques clear and the psoriatic arthritis to just the odd twinge
It's not always the easiest drug to take (I won't sugar coat it) at the start you can have bad side effects and running to the loo is one of them abdominal cramps and flushing are also common at the start of treatment . The side effects if you get them do get better as your body adjusts....but and it's a big but.... if it works as it has for me and lots of other people it can give you long term clearance (for me 7 yesrs to date ) I would say worth a try if they let you try and with monitoring it's a very safe drug ...I rarely get ill when there's infections about just get the odd cold and haven't had any side effects apart from the odd flush for years

I hope you get something that works well for you without too many side effects

[Fred]

That is a shame Duncan, but like Jim said you gave it a good try.

When you say "Limited to oral" I don't know of any reason not to use a bio with high blood pressure, but your dermatologist is best to advise on that.

As for liking a drink, there is no reason to avoid alcohol whilst on a Bio. I'm testament to that as are people like Dave.

But it's your choice at the end of the day and I wish you good luck with your next treatment.

[Duncan]

Had to come off it in the end. Going to the toilet 7 or 8 times a day. It got worse not better.
My skin was starting to look good. Even my joints felt better than ever.
I even ended up with slight swelling in my lower legs. Just had to come off it. I gave it 1 hell of a go but went through hell and back. I really wanted them to work.
Back to Hospital this week. Limited to oral as I have high blood pressure and drink

Hi Duncan I agree you gave it a good try and the sad thing is that it worked but caused so many other problems
Can I suggest when seeing the dermatologist this week that you ask about skilarence it's the same drug that I'm on but licenced and approved for use here in the UK I find it keeps the plaques clear and the psoriatic arthritis to just the odd twinge
It's not always the easiest drug to take (I won't sugar coat it) at the start you can have bad side effects and running to the loo is one of them abdominal cramps and flushing are also common at the start of treatment . The side effects if you get them do get better as your body adjusts....but and it's a big but.... if it works as it has for me and lots of other people it can give you long term clearance (for me 7 yesrs to date ) I would say worth a try if they let you try and with monitoring it's a very safe drug ...I rarely get ill when there's infections about just get the odd cold and haven't had any side effects apart from the odd flush for years

I hope you get something that works well for you without too many side effects

I was looking at Skilarene as my next choice. Only down side I can see is, 1 in 10,000 bet blood cancer. rather have bad skin than that.
Very low odds but so was getting a rash from Otezla, but I was the one who got it

[Duncan]

That is a shame Duncan, but like Jim said you gave it a good try.

When you say "Limited to oral" I don't know of any reason not to use a bio with high blood pressure, but your dermatologist is best to advise on that.

As for liking a drink, there is no reason to avoid alcohol whilst on a Bio. I'm testament to that as are people like Dave.

But it's your choice at the end of the day and I wish you good luck with your next treatment.

I cant find where I said "limited to oral"
This was my first oral treatment. I know they wont use Bio until all oral has been ruled out.
Something I havnt looked into much. Is it any safer/ side effects?

[Fred]

That is a shame Duncan, but like Jim said you gave it a good try.

When you say "Limited to oral" I don't know of any reason not to use a bio with high blood pressure, but your dermatologist is best to advise on that.

As for liking a drink, there is no reason to avoid alcohol whilst on a Bio. I'm testament to that as are people like Dave.

But it's your choice at the end of the day and I wish you good luck with your next treatment.

I cant find where I said "limited to oral"
This was my first oral treatment. I know they wont use Bio until all oral has been ruled out.
Something I havnt looked into much. Is it any safer/ side effects?

Sorry I must have missunderstood you, but It was in this post: RE: Otezla and rash

"Limited to oral as I have high blood pressure and drink"

Yes they will probably make you try another oral as that was your first, you can find them all here: Oral Treatments For Psoriasis

And the Bio's are here: Biological Treatments For Psoriasis

As for which is safer or have worse side effects. All treatments have their problems as you are messing with your body, some like me will never use Methotrexate and some on the other hand will never use Bio's. I choose Bio's because they gave me my life back.

Don't forget to start a new thread once you do go onto your next step.

[jiml]

Had to come off it in the end. Going to the toilet 7 or 8 times a day. It got worse not better.
My skin was starting to look good. Even my joints felt better than ever.
I even ended up with slight swelling in my lower legs. Just had to come off it. I gave it 1 hell of a go but went through hell and back. I really wanted them to work.
Back to Hospital this week. Limited to oral as I have high blood pressure and drink

Hi Duncan I agree you gave it a good try and the sad thing is that it worked but caused so many other problems
Can I suggest when seeing the dermatologist this week that you ask about skilarence it's the same drug that I'm on but licenced and approved for use here in the UK I find it keeps the plaques clear and the psoriatic arthritis to just the odd twinge
It's not always the easiest drug to take (I won't sugar coat it) at the start you can have bad side effects and running to the loo is one of them abdominal cramps and flushing are also common at the start of treatment . The side effects if you get them do get better as your body adjusts....but and it's a big but.... if it works as it has for me and lots of other people it can give you long term clearance (for me 7 yesrs to date ) I would say worth a try if they let you try and with monitoring it's a very safe drug ...I rarely get ill when there's infections about just get the odd cold and haven't had any side effects apart from the odd flush for years

I hope you get something that works well for you without too many side effects

I was looking at Skilarene as my next choice. Only down side I can see is, 1 in 10,000 bet blood cancer. rather have bad skin than that.
Very low odds but so was getting a rash from Otezla, but I was the one who got it

I think the risk is so low and with monitoring of your blood levels as I have done if any abnormalities are seen they should be able to rectify with dose adjustment or cessation
But it's up to you I think the risks are way lower than those of methotrexate
See this post what Biogen that make fumaderm the same active ingredient as skilarence had to say when I asked about cancer  RE: Fumaderm and hormone injections

[Duncan]

Had to come off it in the end. Going to the toilet 7 or 8 times a day. It got worse not better.
My skin was starting to look good. Even my joints felt better than ever.
I even ended up with slight swelling in my lower legs. Just had to come off it. I gave it 1 hell of a go but went through hell and back. I really wanted them to work.
Back to Hospital this week. Limited to oral as I have high blood pressure and drink

Hi Duncan I agree you gave it a good try and the sad thing is that it worked but caused so many other problems
Can I suggest when seeing the dermatologist this week that you ask about skilarence it's the same drug that I'm on but licenced and approved for use here in the UK I find it keeps the plaques clear and the psoriatic arthritis to just the odd twinge
It's not always the easiest drug to take (I won't sugar coat it) at the start you can have bad side effects and running to the loo is one of them abdominal cramps and flushing are also common at the start of treatment . The side effects if you get them do get better as your body adjusts....but and it's a big but.... if it works as it has for me and lots of other people it can give you long term clearance (for me 7 yesrs to date ) I would say worth a try if they let you try and with monitoring it's a very safe drug ...I rarely get ill when there's infections about just get the odd cold and haven't had any side effects apart from the odd flush for years

I hope you get something that works well for you without too many side effects

I was looking at Skilarene as my next choice. Only down side I can see is, 1 in 10,000 bet blood cancer. rather have bad skin than that.
Very low odds but so was getting a rash from Otezla, but I was the one who got it

I think the risk is so low and with monitoring of your blood levels as I have done if any abnormalities are seen they should be able to rectify with dose adjustment or cessation
But it's up to you I think the risks are way lower than those of methotrexate
See this post what Biogen that make fumaderm the same active ingredient as skilarence had to say when I asked about cancer  RE: Fumaderm and hormone injections

So is Fumaderm the same as Skilarence? Or have I miss read it. Reassuring reading the reply. Thanks

[jiml]

Had to come off it in the end. Going to the toilet 7 or 8 times a day. It got worse not better.
My skin was starting to look good. Even my joints felt better than ever.
I even ended up with slight swelling in my lower legs. Just had to come off it. I gave it 1 hell of a go but went through hell and back. I really wanted them to work.
Back to Hospital this week. Limited to oral as I have high blood pressure and drink

Hi Duncan I agree you gave it a good try and the sad thing is that it worked but caused so many other problems
Can I suggest when seeing the dermatologist this week that you ask about skilarence it's the same drug that I'm on but licenced and approved for use here in the UK I find it keeps the plaques clear and the psoriatic arthritis to just the odd twinge
It's not always the easiest drug to take (I won't sugar coat it) at the start you can have bad side effects and running to the loo is one of them abdominal cramps and flushing are also common at the start of treatment . The side effects if you get them do get better as your body adjusts....but and it's a big but.... if it works as it has for me and lots of other people it can give you long term clearance (for me 7 yesrs to date ) I would say worth a try if they let you try and with monitoring it's a very safe drug ...I rarely get ill when there's infections about just get the odd cold and haven't had any side effects apart from the odd flush for years

I hope you get something that works well for you without too many side effects

I was looking at Skilarene as my next choice. Only down side I can see is, 1 in 10,000 bet blood cancer. rather have bad skin than that.
Very low odds but so was getting a rash from Otezla, but I was the one who got it

I think the risk is so low and with monitoring of your blood levels as I have done if any abnormalities are seen they should be able to rectify with dose adjustment or cessation
But it's up to you I think the risks are way lower than those of methotrexate
See this post what Biogen that make fumaderm the same active ingredient as skilarence had to say when I asked about cancer  RE: Fumaderm and hormone injections

So is Fumaderm the same as Skilarence? Or have I miss read it. Reassuring reading the reply. Thanks

Yes it's the same working ingredient DMF but fumaderm has a few other salts in that do nothing for the psoriasis ...skilarence is pure and if I get the chance I will switch to it
I hope if you can get it it will make a huge difference, I'm over 70 now and have suffered all my life with psoriasis and have had things that work for a while, had far to much steroid ointment and UV treatment which are all very short term fixes , since being on Fumaderm (DMF) it has transformed my life and now have far more confidence and no longer have to keep covered up and days at the beach are a pleasure instead of a nightmare

[Kat]

Sorry you had to give up on the Otezla, but as you said you gave it a good try!

I hope your next treatment is kinder to you on the side effects.