Health Boards
Tue-23-02-2016, 20:47 PM
I know what nuber 10 is :
![[Image: p12004.gif]](https://Dead%20image/psmile/med/p12004.gif)
Injection time
Injection time
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Low energy levels on fumaderm
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Tue-23-02-2016, 20:51 PM
(Tue-23-02-2016, 20:36 PM)Caroline Wrote:(Tue-23-02-2016, 20:32 PM)braye lodge Wrote:(Tue-23-02-2016, 20:25 PM)jiml Wrote: No you've not done anything wrong it but your question would be more visible in a thread of its own Was number 10 Jim was right 
Tue-23-02-2016, 20:53 PM
(Tue-23-02-2016, 20:51 PM)jiml Wrote:You put up a good fight jim(Tue-23-02-2016, 20:36 PM)Caroline Wrote:(Tue-23-02-2016, 20:32 PM)braye lodge Wrote:(Tue-23-02-2016, 20:25 PM)jiml Wrote: No you've not done anything wrong it but your question would be more visible in a thread of its own
Tue-23-02-2016, 20:54 PM
(Tue-23-02-2016, 20:53 PM)braye lodge Wrote:(Tue-23-02-2016, 20:51 PM)jiml Wrote:You put up a good fight jim(Tue-23-02-2016, 20:36 PM)Caroline Wrote:(Tue-23-02-2016, 20:32 PM)braye lodge Wrote:(Tue-23-02-2016, 20:25 PM)jiml Wrote: No you've not done anything wrong it but your question would be more visible in a thread of its own  .... I have to with Caroline or she gets the whip out 
Tue-23-02-2016, 20:54 PM
(Tue-23-02-2016, 20:51 PM)jiml Wrote:(Tue-23-02-2016, 20:36 PM)Caroline Wrote:(Tue-23-02-2016, 20:32 PM)braye lodge Wrote:(Tue-23-02-2016, 20:25 PM)jiml Wrote: No you've not done anything wrong it but your question would be more visible in a thread of its own Jim was partly right. It is not as bad as it seems.  So: ![[Image: 17946120019_0dff209b55_o.jpg]](https://farm8.staticflickr.com/7759/17946120019_0dff209b55_o.jpg)
Fri-26-02-2016, 09:51 AM
It was the case of the patient with a 0.8 count getting PML that caused the concern. There is also concern that the JC virus may also act more slowly and cause dementia over a longer period. I stress this is speculative, but now that DMF is being used on large numbers of patients the uncommon side effects can be a problem. Personally I find DMF to be neuroprotective, but I wouldn't go as far as saying that the caution is an over-reaction. It would be nice if MTX were treated with the same level of concern instead of presenting statistical marvels to show how great it is.
Fri-26-02-2016, 10:09 AM
(Fri-26-02-2016, 09:51 AM)Bill Wrote: It was the case of the patient with a 0.8 count getting PML that caused the concern. There is also concern that the JC virus may also act more slowly and cause dementia over a longer period. I stress this is speculative, but now that DMF is being used on large numbers of patients the uncommon side effects can be a problem. Personally I find DMF to be neuroprotective, but I wouldn't go as far as saying that the caution is an over-reaction. It would be nice if MTX were treated with the same level of concern instead of presenting statistical marvels to show how great it is. I think it's better to warn and point out facts, if they are available and then let people make up their own minds. How to deal with them I know the cases are rare but that doesn't mean you should put yourself at risk by maintaining a low lymphocyte count, and not take any action i.e. Reduce dose or retest blood levels . I agree that there should be more warning about methotrexate. But the problems caused by that are more or less ignored |
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