Sun-04-12-2016, 06:49 AM
I read all the Low Dose Naltrexone posts on the site and enjoyed them thoroughly--they've all been closed for good reasons/false promises. I'm new here, but as Fred can already tell, I'm basically a mad scientist much too willing to make leaps from my own experiences as a patient and health care provider into the unknown. I've been on LDN off and on for a year or so. Much like DMF, it has also been studied in multiple sclerosis. It causes the body to notice a slight depletion in endorphins and make more to compensate. This in turn boosts immunity. A full dose would be only be useful to decouple morphine or heroin from mu receptors.
It has made a slight difference with my skin issues that is sometimes only apparent if I stop taking it for a while. More specifically, I seem to have fewer serious/random outbreaks. It is cheap and I found it easy to create a water soluble solution with for simple dosing of 3mg nightly. I don't feel it would be worth the effort to crush and pack little capsules with. I felt wired at first and had to increase the dose 1 mg per week at a time (5mg LDN is generally a max dose). The only long term side effect is vivid dreams, which I find fun.
I think LDN makes the most sense if coming off biologicals, but as a stand alone therapy it may not be adequate. It sure hasn't been for me. Of course, boosting immunity is a positive effect regardless. Because of the complexity of auto-immune issues, it could be theoretically possible to take LDN even while on immune-supressants (think of a patient on chemo eating a healthy, anti-oxidant diet), but of course the more likely effect is that they would cancel each other out.
It has made a slight difference with my skin issues that is sometimes only apparent if I stop taking it for a while. More specifically, I seem to have fewer serious/random outbreaks. It is cheap and I found it easy to create a water soluble solution with for simple dosing of 3mg nightly. I don't feel it would be worth the effort to crush and pack little capsules with. I felt wired at first and had to increase the dose 1 mg per week at a time (5mg LDN is generally a max dose). The only long term side effect is vivid dreams, which I find fun.
I think LDN makes the most sense if coming off biologicals, but as a stand alone therapy it may not be adequate. It sure hasn't been for me. Of course, boosting immunity is a positive effect regardless. Because of the complexity of auto-immune issues, it could be theoretically possible to take LDN even while on immune-supressants (think of a patient on chemo eating a healthy, anti-oxidant diet), but of course the more likely effect is that they would cancel each other out.