Wed-13-07-2016, 19:39 PM
"The latest study on LDN 6/16, found that LDN upregulates a unique set of gene expressions not seen with normal doses. LDN had a selective impact on genes involved with cell cycle regulation and immune modulation."
The reason I make mention of this study besides a thirst for knowledge and its recent publication is,... how it might have implications for us psoriasis patients.
This study was observed on cancer cell lines. But if it showed an upregulation of genes involved with cell cycle regulation and immune modulation, you could see how this would benefit psoriasis also.
Psoriasis is an unregulated growth of skin cells. Producing skin cells in a day that would normally take a month or there abouts. So cell cycle regulation, (which is the process of proliferation and growth of cells), being modified through gene expression, might have a major impact in those with psoriasis. Not to mention LDN's effects on genes, involved with immune modulation. Possibly correcting or modulating a dysfunctional immune response as in autoimmunity.
So here we have two distinct pathways in which LDN might possibly benefit those with psoriasis as well as with cancer.
My mind continues to think things through.
The reason I make mention of this study besides a thirst for knowledge and its recent publication is,... how it might have implications for us psoriasis patients.
This study was observed on cancer cell lines. But if it showed an upregulation of genes involved with cell cycle regulation and immune modulation, you could see how this would benefit psoriasis also.
Psoriasis is an unregulated growth of skin cells. Producing skin cells in a day that would normally take a month or there abouts. So cell cycle regulation, (which is the process of proliferation and growth of cells), being modified through gene expression, might have a major impact in those with psoriasis. Not to mention LDN's effects on genes, involved with immune modulation. Possibly correcting or modulating a dysfunctional immune response as in autoimmunity.
So here we have two distinct pathways in which LDN might possibly benefit those with psoriasis as well as with cancer.
My mind continues to think things through.