Fri-06-02-2015, 20:23 PM
(Fri-06-02-2015, 20:20 PM)Caroline Wrote:I will have a read Caroline ,do you have any monitoring process though to make sure all is well. MTX is much older than 30 years in fact I believe that it's over 50 years since they started using it.(Fri-06-02-2015, 20:11 PM)D Foster Wrote:(Fri-06-02-2015, 11:20 AM)Caroline Wrote:As far as I am aware Caroline DMF is not approved in UK though I will stand to be corrected, I have been looking at it and it would appear to be not fully understood how it works . Do you have blood checks to make sure that after taking it everything is OK ?(Fri-06-02-2015, 09:27 AM)D Foster Wrote:(Fri-06-02-2015, 07:46 AM)Caroline Wrote: I still don't agree with you Dave. There are still better ways to go.
I took MTX for 9 years ,6 by mouth and 3 by self injection and even though I am on 90mg of Stelara the relief for my PsA was much better on MTX.The side effects were not good towards the end of the tablets then on injection that settled down but built up again so I came off it however for the P it never cleared it but as I said for the PsA yes it was good. I can think of many other treatments that are worse and if you are very careful and monitor it then it is OK , PsA is extremely painful and I am lucky because I am not as bad as Fred.I take Tramadol and would argue that this is as bad as MTX in many ways especially as it only masks the pain leaving the joints alone which MTX does effect. A catch 22 situation prevails so where do you go ,it's just a matter of trying to play it safe as you can to get some relief.
I took MTX for three weeks. After that three weeks, there was only one thing in my mind. "I don't wanna die so young, I must get rid of this stuff"....
So I had the luck to stumble upon DMF, which you have not used , upto now I am very lucky with that.
It appears to be very good at removing mould from leather ! I took Cyclosporine and that had the same effect on me as MTX had on you , what works for one does not work for another as we all react in a different way. There are not many treatments that I have not had over the many years I have had this dam problem ,I had one on a trail that I cannot remember what it was called that caused my toe nails to grow through the side of my toe and that was quite painful.
Dave, read my thread on dimethylfumarates and psoriasis, and you will know more.
Approval is an adminisitrative process, this is a medication that is already more than 30 years old. It has proven itself in practice, that is the real importance.