Health Boards
Sat-26-04-2014, 13:31 PM
Hi Caroline,
From a toxicity study I read, DMF at 5 mg/kg/day given to monkeys caused no harm, whereas at 25 mg/kg/day and higher adverse changes in organs were noted. I'd be interested to see studies at 10 and 15, as these are closer to the therapeutic range, but as you point out, monitoring is essential.
The side effects I had were bad, but I have read accounts of people on Fumaderm who seemed to find it tougher than me. Isabelle's experience is one example. Taking the drug with food is very important, but that wont spare you the side effects of the monomethyl fumarate, which for me included severe headaches.
Cheers,
Bill
From a toxicity study I read, DMF at 5 mg/kg/day given to monkeys caused no harm, whereas at 25 mg/kg/day and higher adverse changes in organs were noted. I'd be interested to see studies at 10 and 15, as these are closer to the therapeutic range, but as you point out, monitoring is essential.
The side effects I had were bad, but I have read accounts of people on Fumaderm who seemed to find it tougher than me. Isabelle's experience is one example. Taking the drug with food is very important, but that wont spare you the side effects of the monomethyl fumarate, which for me included severe headaches.
Cheers,
Bill