About to start Fumaderm

[Bill]

Once you have been on the drug a few months and have developed no liver or kidney problems, it is a matter of balancing efficacy with a safe lymphocyte count. I am not so convinced of the slow release concept as I take a large dose of 99% DMF (~830mg) twice weekly. I get greater efficacy for both p and psa with this dose than I would with three daily doses of 240mg. If the slow release concept were valid, I would expect that a number of small doses would be more effective than a large dose over a set time. For me this is not the case. I have tried a number of different doses. A little over 800mg is optimal. Larger doses have greater side effects with a less than proportional increase in efficacy. Smaller doses have a greater than proportional drop in efficacy. But if DMF does not work, try something else.