Sun-11-06-2017, 00:32 AM
Hi Nico,
I started with 3*240 mg daily, and yes, it was no fun, but it did reduce my disease activity quickly. With the benefit of hindsight I would have started with a 200 mg twice weekly dose, increasing the dosage weekly provided it was being tolerated. Incremental buildup has the obvious advantage of allowing you to build up your tolerance of the drug, but as there is variance in the therapeutic dosage for individuals, it will also allow your dermatologist to determine this value for you. If your disease responds well, the dosage can often be reduced (maintenance dose). There is one member on this forum maintaining his clearance with 120 mg of DMF taken every third day.
Good luck with your treatment.
I started with 3*240 mg daily, and yes, it was no fun, but it did reduce my disease activity quickly. With the benefit of hindsight I would have started with a 200 mg twice weekly dose, increasing the dosage weekly provided it was being tolerated. Incremental buildup has the obvious advantage of allowing you to build up your tolerance of the drug, but as there is variance in the therapeutic dosage for individuals, it will also allow your dermatologist to determine this value for you. If your disease responds well, the dosage can often be reduced (maintenance dose). There is one member on this forum maintaining his clearance with 120 mg of DMF taken every third day.
Good luck with your treatment.