Posts: 71,229
Threads: 4,130
Joined: Aug 2011
Gender: Male
Location: France
Psoriasis Score: Zero
Psoriatic Arthritis Score: 1
PQOLS: 1
Treatment: Bimzelx / Coconut Oil
(Mon-08-07-2019, 20:04 PM)Caroline Wrote: (Mon-08-07-2019, 12:36 PM)Bill Wrote: I still think you should have taken the Fumaderm, Jim.
OBI, what is the formulation of Skilarence? So much for the manufacturer claiming gastro-resistant tablets. Are you sure it is your stomach being irritated? I reduce my side effects by drinking plenty of water in the hours before dosing and taking the drug after a meal so it will mix well with my stomach contents.
Cheers
Bill,
Skilarence has a stomach resistant coating. Obi has intestine cramps.
Inside are (in Dutch but I think readable)
Lactosemonohydraat Microkristallijne cellulose Croscarmellose natrium Colloïdaal watervrij silica Magnesiumstearaat
Pssssssst: [thread=5165]
Quote:
What Skilarence 120 mg contains
- the active substance is dimethyl fumarate. One tablet contains 120 mg dimethyl fumarate. - the other ingredients are: lactose monohydrate, cellulose microcrystalline, croscarmellose
sodium, colloidal anhydrous silica, magnesium stearate, methacrylic acid-ethyl acrylate copolymer (1:1), talc, triethyl citrate, titanium dioxide (E171), simethicone, indigo carmine (E132) and sodium hydroxide.
Posts: 28,484
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Joined: Nov 2011
Gender: Female
Location: In between the tulips
Psoriasis Score: 3
Psoriatic Arthritis Score: 3
PQOLS: 4
Treatment: Got back to DMF slow release
(Mon-08-07-2019, 20:10 PM)Fred Wrote: (Mon-08-07-2019, 20:04 PM)Caroline Wrote: (Mon-08-07-2019, 12:36 PM)Bill Wrote: I still think you should have taken the Fumaderm, Jim.
OBI, what is the formulation of Skilarence? So much for the manufacturer claiming gastro-resistant tablets. Are you sure it is your stomach being irritated? I reduce my side effects by drinking plenty of water in the hours before dosing and taking the drug after a meal so it will mix well with my stomach contents.
Cheers
Bill,
Skilarence has a stomach resistant coating. Obi has intestine cramps.
Inside are (in Dutch but I think readable)
Lactosemonohydraat Microkristallijne cellulose Croscarmellose natrium Colloïdaal watervrij silica Magnesiumstearaat
Pssssssst: [thread=5165]
Quote:
What Skilarence 120 mg contains
- the active substance is dimethyl fumarate. One tablet contains 120 mg dimethyl fumarate. - the other ingredients are: lactose monohydrate, cellulose microcrystalline, croscarmellose
sodium, colloidal anhydrous silica, magnesium stearate, methacrylic acid-ethyl acrylate copolymer (1:1), talc, triethyl citrate, titanium dioxide (E171), simethicone, indigo carmine (E132) and sodium hydroxide.
Much better.... 
Posts: 71,229
Threads: 4,130
Joined: Aug 2011
Gender: Male
Location: France
Psoriasis Score: Zero
Psoriatic Arthritis Score: 1
PQOLS: 1
Treatment: Bimzelx / Coconut Oil
(Mon-08-07-2019, 20:11 PM)Caroline Wrote: (Mon-08-07-2019, 20:10 PM)Fred Wrote: (Mon-08-07-2019, 20:04 PM)Caroline Wrote: (Mon-08-07-2019, 12:36 PM)Bill Wrote: I still think you should have taken the Fumaderm, Jim.
OBI, what is the formulation of Skilarence? So much for the manufacturer claiming gastro-resistant tablets. Are you sure it is your stomach being irritated? I reduce my side effects by drinking plenty of water in the hours before dosing and taking the drug after a meal so it will mix well with my stomach contents.
Cheers
Bill,
Skilarence has a stomach resistant coating. Obi has intestine cramps.
Inside are (in Dutch but I think readable)
Lactosemonohydraat Microkristallijne cellulose Croscarmellose natrium Colloïdaal watervrij silica Magnesiumstearaat
Pssssssst: [thread=5165]
Quote:
What Skilarence 120 mg contains
- the active substance is dimethyl fumarate. One tablet contains 120 mg dimethyl fumarate. - the other ingredients are: lactose monohydrate, cellulose microcrystalline, croscarmellose
sodium, colloidal anhydrous silica, magnesium stearate, methacrylic acid-ethyl acrylate copolymer (1:1), talc, triethyl citrate, titanium dioxide (E171), simethicone, indigo carmine (E132) and sodium hydroxide.
Much better....
We have a lot of information on Psoriasis Club. 
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
Thank you Fred and Caroline. The longer I self-treat the less I feel that I could benefit from the expertise of the pharmaceutical industry by doing otherwise. OBI, you might like to write to Almirall and tell them how crap their Skilarence is compared to Fumaderm. It will be interesting to see whether Jim fares better: At least he is already on DMF, so he will not have to get used to it.
Cheers
Posts: 47,972
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Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
Hi Bill I collected my Tablets today enough for 2 months but will finish the Fumaderm I have before switching .... So the switchover for me will be in a couple of weeks 
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
Good luck, Jim. I doubt you will have a problem, especially as I am taking 530mg of the raw stuff per dose with little problem.
Cheers
Posts: 47,972
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Joined: Oct 2013
Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
(Wed-10-07-2019, 12:57 PM)Bill Wrote: Good luck, Jim. I doubt you will have a problem, especially as I am taking 530mg of the raw stuff per dose with little problem.
Cheers
Thanks Bill I'm sure you are right can't wait to get onto them now
Posts: 4,813
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Treatment: Waiting a decsion
Good luck with the Skilarence Jim.
I'm hoping you will be able to set me some pointers after I have seen the Dermy in August and convinced them it may be the way to go.
Posts: 47,972
Threads: 357
Joined: Oct 2013
Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
(Wed-10-07-2019, 15:29 PM)JohnB Wrote: Good luck with the Skilarence Jim.
I'm hoping you will be able to set me some pointers after I have seen the Dermy in August and convinced them it may be the way to go.
I would ask for it John I don't think I'm going to have any problem, I will start the first week with one less tablet a day in case for any reason there's a reaction
If you do get it you will have to start on the 30mg tablets and build up gently to minimise the expected side effects
Posts: 47,972
Threads: 357
Joined: Oct 2013
Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
Ok here I go
![[Image: gPH6DxW.jpg]](https://i.imgur.com/gPH6DxW.jpg)
So 9am today I have started the Skilarence tablets we will see later today if they have any side effects for me
Dose will be same as I was on with fumaderm 3x120mg tablets in the morning with breakfast
And 2x 120mg tablets in the evening with my evening meal
I had my bloods done at the beginning of the month and my lymphocyte count was at 1.08 so far enough inside the normal ( between 1.00 and 3.00) to be happy
So it's wait and see what happens, and I'm hoping nothing will change
I will update regularly with any changes I notice
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