Body roundness index and Psoriasis

[Fred]

This study found a non-linear positive relation between body roundness index (BRI) and Psoriasis (Pso)

Quote:

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Background and Aims:
The prevalence of psoriasis (Pso), a chronic immune-mediated inflammatory skin disease, is high in patients with obesity. This study investigates the mediating role of the systemic immune-inflammation index (SII) in the association between body roundness index (BRI) and Pso prevalence.

Methods and Results:
This study included 14,669 participants from the National Health and Nutrition Examination Survey (NHANES) (2003–2006, 2009−2014). The presence or absence of obesity was identified using the BRI, and Pso was assessed using the Pso questionnaire. The association of BRI with Pso was explored by weighted multivariate logistic regression analyses and restricted cubic spline (RCS) analyses, and the threshold effect was further examined using two-stage linear regression models. Mediation analyses assessed SII’s role in the BRI-Pso association. The Pso group included 445 out of 14,669 participants. Logistic regression analyses indicated a positive association between BRI and Pso after adjusting for potential confounders. RCS analyses showed a nonlinear relation between BRI and Pso (Pnonlinear = 0.018), with a point of inflection at 5.103 (odds ratio [OR] = 1.09, 95% CI: 1.04, 1.14). BRI and Pso were positively correlated on the left side of the point of inflection (OR = 1.25, 95% CI: 1.09, 1.45), whereas such an association was not detected on the right side (OR = 1.04, 95% CI: 0.97, 1.11). Mediation analysis showed SII partially mediated this association, accounting for 9.48% of the effect (p < 0.001).

Conclusion:
BRI is positively associated with Pso, with SII playing a mediating role. These findings highlight the importance of visceral fat management and SII monitoring in addressing Pso and its metabolic comorbidities.

Source: onlinelibrary.wiley.com

*Funding: Dengfeng Project of the Beijing High-level Innovation and Entrepreneurship Talent Support Program. National Natural Science Foundation of China.

[Turnedlight]

body roundness! How polite!

[Fred]

    body roundness! How polite!

Yes I thought that.

[mataribot]

How high on the body roundness index does it take to be able to roll down the street? What earth are we doing here?

[Caroline]

How high on the body roundness index does it take to be able to roll down the street? What earth are we doing here?

BRI seems to be a quite new indicator… My guess is that it is also “validated” and “copyrighted”… a lot of Pso and PsA indicators are protected by copyrights, while they are too simple to think of… e.g. the PEST for measuring PsA is containing 5 questions that are copyrighted and it you read them they are utterly simple and could easily pass by in a conversation between us.

[Fred]

How high on the body roundness index does it take to be able to roll down the street? What earth are we doing here?

That would depend if you are barrel or ball shaped, a ball would do better as a barrel would veer to the left or right.

[Turnedlight]

How high on the body roundness index does it take to be able to roll down the street? What earth are we doing here?

That would depend if you are barrel or ball shaped, a ball would do better as a barrel would veer to the left or right.

How about a ball with legs sticking out

[mataribot]

Yawn. where is the real studies that looking to permanently get rid of the disease.