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Psoriasis Club › HealthHealth Boards › Psoriasis In The News v
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Taltz 5 year study

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Taltz 5 year study
Caroline Offline
You must hurry if you ever want to catch a chicken...
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#11
Sat-03-02-2024, 21:37 PM
(Sat-03-02-2024, 14:35 PM)Kat Wrote: Smile

I agree with Mataribot though, still doesn't sound like a great result.

I think this is an interesting subject. So I did some research and therefore I do not agree with Matarbot.

the research I found comes from a meta analysis done in 2018, found on pub med.

Quote: “ The drug survival for all biologics decreased with time, dropping from 66% at year 1 to 41% at year 4 for etanercept, from 69% to 47% for adalimumab, from 61% to 42% for infliximab, and from 82% to 56% for ustekinumab. Ustekinumab was associated with the highest drug survival in all and biologic-naïve subjects.”

So in fact a drug-survival rate of 2/3 = 66% Is quite average, even on the better side.
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mataribot Offline
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#12
Tue-06-02-2024, 04:16 AM
(Sat-03-02-2024, 21:37 PM)Caroline Wrote:
(Sat-03-02-2024, 14:35 PM)Kat Wrote: Smile

I agree with Mataribot though, still doesn't sound like a great result.

I think this is an interesting subject. So I did some research and therefore I do not agree with Matarbot.

the research I found comes from a meta analysis done in 2018, found on pub med.

Quote: “ The drug survival for all biologics decreased with time, dropping from 66% at year 1 to 41% at year 4 for etanercept, from 69% to 47% for adalimumab, from 61% to 42% for infliximab, and from 82% to 56% for ustekinumab. Ustekinumab was associated with the highest drug survival in all and biologic-naïve subjects.”

So in fact a drug-survival rate of 2/3 = 66% Is quite average, even on the better side.

I am going to eat my words on this one and completely agree. A 2/3 survival rate is in line with other biological therapies and significantly better than older treatments. In conclusion, I think there is room for significant improvement in the long term viability of treatments.
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Caroline Offline
You must hurry if you ever want to catch a chicken...
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Posts: 26,472
Threads: 113
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Gender: Female
Location: In between the tulips
Psoriasis Score: 3
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PQOLS: 4
Treatment: Got back to DMF slow release
#13
Tue-06-02-2024, 08:54 AM
(Tue-06-02-2024, 04:16 AM)mataribot Wrote:
(Sat-03-02-2024, 21:37 PM)Caroline Wrote:
(Sat-03-02-2024, 14:35 PM)Kat Wrote: Smile

I agree with Mataribot though, still doesn't sound like a great result.

I think this is an interesting subject. So I did some research and therefore I do not agree with Matarbot.

the research I found comes from a meta analysis done in 2018, found on pub med.

Quote: “ The drug survival for all biologics decreased with time, dropping from 66% at year 1 to 41% at year 4 for etanercept, from 69% to 47% for adalimumab, from 61% to 42% for infliximab, and from 82% to 56% for ustekinumab. Ustekinumab was associated with the highest drug survival in all and biologic-naïve subjects.”

So in fact a drug-survival rate of 2/3 = 66% Is quite average, even on the better side.

I am going to eat my words on this one and completely agree. A 2/3 survival rate is in line with other biological therapies and significantly better than older treatments. In conclusion, I think there is room for significant improvement in the long term viability of treatments.

Now. I agree with you Mataribot Smile Smile
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Kat Offline
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#14
Tue-06-02-2024, 12:28 PM (This post was last modified: Tue-06-02-2024, 12:29 PM by Kat. Edited 2 times in total.)
I agree there's room for improvement as average isn't good enough.  Tongue
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