Posts: 6
Threads: 2
Joined: Jul 2019
Gender: Male
Location: Uk
Treatment: Skilarence
Skilerance is a great drug and works but the side affects for me on 120 mg is not bearable.
I've tried it with food and yogurt, I've even cut the tablet in half and hid it in a soft sweet and swallowed half in the morning and half late afternoon but the cramps i get and sweats and going red is crazy.
I need to inform my dermatologist but after being on methotrexate and cyclosporine, I don't now what other options I have.
Any suggestions would be welcome as i'm sure you all know how i'm feeling.
Posts: 47,972
Threads: 357
Joined: Oct 2013
Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
Mon-23-09-2019, 19:56 PM
(This post was last modified: Mon-23-09-2019, 19:57 PM by jiml.)
(Mon-23-09-2019, 19:40 PM)Fasteddie155 Wrote: Skilerance is a great drug and works but the side affects for me on 120 mg is not bearable.
I've tried it with food and yogurt, I've even cut the tablet in half and hid it in a soft sweet and swallowed half in the morning and half late afternoon but the cramps i get and sweats and going red is crazy.
I need to inform my dermatologist but after being on methotrexate and cyclosporine, I don't now what other options I have.
Any suggestions would be welcome as i'm sure you all know how i'm feeling.
Shame it's not for you and you have given it a fair try ..I'm gutted for you ...I will just say that the side effects do improve with time but for you they are unbearable ...but it's not the end there are many options the dermatologist can give you there are a whole raft of biological drugs for you to try and I'm sure one of them will be the one to work without the grief of cramps
You can read about biological drugs here [thread=77] and be ready when the dermatologist mentions them
Good luck and do let us know what the dermatologist offers you next
Posts: 71,229
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Location: France
Psoriasis Score: Zero
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PQOLS: 1
Treatment: Bimzelx / Coconut Oil
That is a shame Fasteddie, it can take a while to get the right treatment for you but there are plenty of other things to try. I see Jim has given you a link to the Bio's, I'm a big fan as they gave me back my life.
Have a read up on them and arm yourself with information ready for your next appointment.
Good luck.
Posts: 6
Threads: 2
Joined: Jul 2019
Gender: Male
Location: Uk
Treatment: Skilarence
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
Hi Eddie,
Was it working for you at a lower dose with tolerable side effects? You may be able to continue with 30mg tablets. Some people are very sensitive to the drug.
Cheers
Posts: 6
Threads: 2
Joined: Jul 2019
Gender: Male
Location: Uk
Treatment: Skilarence
(Sat-28-09-2019, 06:33 AM)Bill Wrote: Hi Eddie,
Was it working for you at a lower dose with tolerable side effects? You may be able to continue with 30mg tablets. Some people are very sensitive to the drug.
Cheers
Hi Bill yes the lower dose didn't give me so many side affects but didn't really work either.
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
Well, I guess that would put the kybosh on Skilarence for you, Eddie. Hopefully you will get a go with a biologic drug.
Cheers
Posts: 38
Threads: 8
Joined: Mar 2018
Gender: Male
Location: uk
Treatment: Tildrakizumab (ilumetri)
Posts: 28,484
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Gender: Female
Location: In between the tulips
Psoriasis Score: 3
Psoriatic Arthritis Score: 3
PQOLS: 4
Treatment: Got back to DMF slow release
(Sun-29-09-2019, 10:34 AM)Fasteddie155 Wrote: (Sat-28-09-2019, 06:33 AM)Bill Wrote: Hi Eddie,
Was it working for you at a lower dose with tolerable side effects? You may be able to continue with 30mg tablets. Some people are very sensitive to the drug.
Cheers
Hi Bill yes the lower dose didn't give me so many side affects but didn't really work either.
Probably you belong to the group of people who are too sensitive for it. So a slow release dose would also not help with you, I guess.
Indeed next step will be a biological.
They are probably going to try out some with you.
In the current number of “Psoriasis” the magazine of the Dutch patients community there is an article about the BIOMAP project. A worldwide project which has the purpose to find all the markers that are involved in psoriasis and Psoriatic Arthritis. The ultimate goal is to in the end analyse the blood of a patient and on the base of the markers being able to exactly pinpoint which treatment suits the best for that patient. So you will have a personalised approach and all the trying will not be necessary anymore.
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