Psoriasis treatments of the future

[Fred]

The future of psoriasis treatment is changing, and it's moving along very fast. This past few years have seen a huge increase in the number of Bio treatments and I was wondering how others see the future of psoriasis treatments.

Will it be an oral treatment, a cream, a spray, an injection, a natural treatment or maybe something we have not seen yet ?

As some of you know I have my contacts that pass me the latest information as it happens and I publish it as soon as I know, but I have noticed that most of the stuff I publish recently is concerned with the Bio treatments.

You may also know I'm a big fan of the Bio treatments as they gave me back my life, however I try not to be biased in the news reports so I'm curious to what others think the psoriasis treatment of the future will be.  

Over to you.

[jiml]

The future of psoriasis treatment is changing, and it's moving along very fast. This past few years have seen a huge increase in the number of Bio treatments and I was wondering how others see the future of psoriasis treatments.

Will it be an oral treatment, a cream, a spray, an injection, a natural treatment or maybe something we have not seen yet ?

As some of you know I have my contacts that pass me the latest information as it happens and I publish it as soon as I know, but I have noticed that most of the stuff I publish recently is concerned with the Bio treatments.

You may also know I'm a big fan of the Bio treatments as they gave me back my life, however I try not to be biased in the news reports so I'm curious to what others think the psoriasis treatment of the future will be.  

Over to you.

A good question Fred ....who knows what the future holds for psoriasis sufferers, but the last Decade has seen an explosion of activity in the biological treatments with several novel ones still to hit the market.

The pharmaceutical companies are working at targeting smaller areas of our blood to give less side effects and faster clearance.   I suppose this means they are narrowing the search down to certain T cells and targeting them.

In the future it may be possible to genetically modify these cells to give lifelong clearance, I doubt I will see it but I think the way research is progressing it is just a matter of time.

The sooner the better so we can throw aside some of the dangerous creams and drugs we take

That's what I think ....but I may be way out ....time will tell

[Fred]

A good question Fred ....who knows what the future holds for psoriasis sufferers, but the last Decade has seen an explosion of activity in the biological treatments with several novel ones still to hit the market.

The pharmaceutical companies are working at targeting smaller areas of our blood to give less side effects and faster clearance.   I suppose this means they are narrowing the search down to certain T cells and targeting them.

In the future it may be possible to genetically modify these cells to give lifelong clearance, I doubt I will see it but I think the way research is progressing it is just a matter of time.

The sooner the better so we can throw aside some of the dangerous creams and drugs we take

That's what I think ....but I may be way out ....time will tell

The thing I find difficult is that the old oral treatments especially methotrexate (which we all know the dangers of) have been around for years, yet are still given. Also the amount of people using Dovobet long term when it's designed to be used for 4 weeks only is worrying.

I'm trying to remain unbiased but to be honest the future is looking Bio to me.

[jiml]

A good question Fred ....who knows what the future holds for psoriasis sufferers, but the last Decade has seen an explosion of activity in the biological treatments with several novel ones still to hit the market.

The pharmaceutical companies are working at targeting smaller areas of our blood to give less side effects and faster clearance.   I suppose this means they are narrowing the search down to certain T cells and targeting them.

In the future it may be possible to genetically modify these cells to give lifelong clearance, I doubt I will see it but I think the way research is progressing it is just a matter of time.

The sooner the better so we can throw aside some of the dangerous creams and drugs we take

That's what I think ....but I may be way out ....time will tell

The thing I find difficult is that the old oral treatments especially methotrexate (which we all know the dangers of) have been around for years, yet are still given. Also the amount of people using Dovobet long term when it's designed to be used for 4 weeks only is worrying.

I'm trying to remain unbiased but to be honest the future is looking Bio to me.

I'm sure you are right in the immediate future. It is good to read of the advances being made with the bios, there doesn't seem to be much other research into the idea of gene modification, understandably they are concentrating that research on life threatening diseases, but I'm sure in time it will filter down to auto immune diseases but until then, you are right Bios are the way forward ...... although I love the drug I'm on I can't see it being a front runner in the treatment of the disease,  for the problems people encounter with side effects

[Kat]

That's a tough one. The problem I see with biologics is the cost and until that is driven down, insurance companies will continue to push some of the older (and cheaper) options.

There does seem to be a lot of new biologics being available so for the near future I think that is where things are heading. As for years from now... hard to say.

[Fred]

That's a tough one.  The problem I see with biologics is the cost and until that is driven down, insurance companies will continue to push some of the older (and cheaper) options.  

There does seem to be a lot of new biologics being available so for the near future I think that is where things are heading.  As for years from now... hard to say.

Good point Kat. But if it's free as it is for me in France then the cost is not important, but I can understand for some it could be an issue.

[Bill]

As much as I dont like it, Mtx is a proven and useful drug. It would be unfortunate were it not available. I would also like the therapy to be as specific as possible, but it may be the case that there is more than one target, so combination therapies might have more to offer. DMF has been very effective for me, but as it has been my only systemic treatment I can make no comparison with other therapies. On a cost and safety basis DMF is unsurpassed, but lymphocyte suppression can be a problem and the gi side effects wont make it a crowd pleaser either. I am currently trying folic acid together with zinc and B group vitamins to try and up my lymphocyte count. Perhaps the most important thing with psoriasis is to maintain your sense of adventure!

[jiml]

Perhaps the most important thing with psoriasis is to maintain your sense of adventure!

Indeed Bill and a sense of positivity and humour

[Fred]

Perhaps the most important thing with psoriasis is to maintain your sense of adventure!

Is that in ones choice of treatments or life in general ?