Metabolic syndrome in Lebanese patients with psoriasis

[Fred]

This study looked at the prevalence of metabolic syndrome (MBS) in Lebanese patients with psoriasis.

Quote:

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Background:
Psoriasis is a chronic inflammatory disease that affects not only the skin but also other organs as well. Genetic factors play an important role in individual predisposition. Lately, a positive association has been confirmed between psoriasis and metabolic syndrome (MBS), in western as well as in Middle Eastern countries.

Aim:
Assess the prevalence of MBS in Lebanese patients with psoriasis and the differential effect according to types and disease severity.

Methods:
This was a case-control study including 150 psoriasis patients and 150 age- and gender-matched controls admitted to the dermatology clinics at the American University of Beirut-Medical Center, a tertiary care center in Beirut. Psoriasis severity was assessed by the Psoriasis Area Severity Index (PASI). Blood samples were collected from fasting subjects and tested for glucose, HDL cholesterol, triglycerides, and C-reactive protein (CRP). Multivariate binary logistic regression models were built to assess the relationship between MBS and psoriasis, after adjustment for smoking as a possible confounding variable.

Results:
Patients with psoriasis were two times more likely to have MBS as compared to controls (35.3% vs 18.0%, P < 0.001) with an odds ratio (OR) of 2.4. All components of MBS were more prevalent in psoriasis patients than in controls. PASI score was greater in patients with MBS than those without MBS (10.5 ± 11.5 vs. 7.0 ± 8.1, P = 0.05). MBS prevalence tended to be higher in the inverse type than in others (52.2% versus 32.3%; P = 0.06) and in patients with nail pitting versus those without (45.3% vs. 28.2%; P = 0.03).

Conclusions:
This was the first study to assess the prevalence of MBS in Lebanese subjects with psoriasis and, to our knowledge, the first study that showed a higher likelihood of MBS in patients with inverse psoriasis and with nail pitting.

Source: onlinelibrary.wiley.com

*Early view funding unknown.

[jiml]

That's not good news, but perhaps a wake up call to those of us with a sedentary lifestyle that are overweight
And are likely to develop MBS
Could it be that with psoriasis, as sufferers we tend not to get as much exercise as someone without psoriasis as its not a very " social" disease and many tend to keep themselves isolated and comfort eat.. Causing high blood pressure , obesity and the other things that cause pre diabetes or MBS

Just my thoughts

[Fred]

That's not good news, but perhaps a wake up call to those of us with a sedentary lifestyle that are overweight
And are likely to develop MBS  
Could it be that with psoriasis, as sufferers we tend not to get as much exercise as someone without psoriasis as its not a very " social" disease and many tend to keep themselves isolated and comfort eat.. Causing high blood pressure , obesity and the other things that cause pre diabetes or MBS

Just my thoughts

I would say you're on the right tracks.

#1 Psoriasis makes us self concious so we don't go out so much.

#2 We look for comfort from foods, alcohol, and tobacco.

#3 Exercise can be difficult especially if you have psoriatic arthritis.

We also have another similar study here: Psoriasis and metabolic syndrome

[jiml]

That's not good news, but perhaps a wake up call to those of us with a sedentary lifestyle that are overweight
And are likely to develop MBS  
Could it be that with psoriasis, as sufferers we tend not to get as much exercise as someone without psoriasis as its not a very " social" disease and many tend to keep themselves isolated and comfort eat.. Causing high blood pressure , obesity and the other things that cause pre diabetes or MBS

Just my thoughts

I would say you're on the right tracks.

#1 Psoriasis makes us self concious so we don't go out so much.

#2 We look for comfort from foods, alcohol, and tobacco.

#3 Exercise can be difficult especially if you have psoriatic arthritis.

We also have another similar study here: Psoriasis and metabolic syndrome

That is interesting as both studies have a similar outcome, it is an important finding and should spur us on to exercise more .... Which I can understand is difficult for PsA sufferers
But al least we are more aware of the dangers with you publishing this study

[D Foster]

Very interesting and something to look out for, I am overweight but blood pressure, blood sugar ,cholesterol etc. are all ok .