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Bill Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 1,624
Threads: 6
Joined: Dec 2012
Gender: Male
Location: Queensland
Treatment: Dimethyl fumarate
#141
Sat-31-10-2015, 12:42 PM
Good for you, Bassman. Long term use of medication often results in a squeeze between side effects and efficacy, so you are very fortunate that the maximum dosage is delivering for you. Hopefully you can reduce your dose at some stage. Out of interest, has your specialist concurrently prescribed topicals such as calcipotriol? I have found the use of accessory therapies to be very helpful in controlling the disease and allowing me to take less DMF, which is why I keep experimenting.

Cheers,

Bill
Quote
Fred Offline
I Wanted To Change the World But Got Up Far Too Late.
Moderator
Posts: 66,958
Threads: 3,888
Joined: Aug 2011
Gender: Male
Location: France
Psoriatic Arthritis Score: 1
PQOLS: 1
Treatment: Bimzelx / Coconut Oil
#142
Sat-31-10-2015, 12:42 PM
(Sat-31-10-2015, 12:40 PM)bassman Wrote: I cant believe it Fred

I dont get any notifications for ages, then as soon as i mention it, i get 2, in both threads you mention

Sometimes the system stops sending them if you haven't visited from the last time it sent some.

If it happens again give me a shout. Smile
Quote
bassman Offline Author
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 129
Threads: 3
Joined: Sep 2015
Gender: Male
Location: Oxfordshire
Treatment: fumaderm
#143
Sat-31-10-2015, 12:50 PM (This post was last modified: Sat-31-10-2015, 12:51 PM by bassman.)
(Sat-31-10-2015, 12:42 PM)Bill Wrote: Good for you, Bassman. Long term use of medication often results in a squeeze between side effects and efficacy, so you are very fortunate that the maximum dosage is delivering for you. Hopefully you can reduce your dose at some stage. Out of interest, has your specialist concurrently prescribed topicals such as calcipotriol? I have found the use of accessory therapies to be very helpful in controlling the disease and allowing me to take less DMF, which is why I keep experimenting.

Cheers,

Bill

As i see it Bill, the max dosage of Fuma is more or less what it has taken to get me this far, so as far i'm concerned, i'll not reduce the dose unless i get side effect problems, which is really minimal in my case. At least its minimal in what i feel. I cannot feel what the blood tests are telling me but the doctors will tell me if there's anything untowards going on in the bloods. Like my time on MTX, it was the bloods that said i needed to come off them. I didnt know because i didnt feel anything

If the blood test revealed anythingon Fuma, then yes i would reduce the dose, but i feel this isn't necessary at the moment.

As for Calcitropiol, i've never heard of that and has never been offered to me by any consultant
Quote
bassman Offline Author
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 129
Threads: 3
Joined: Sep 2015
Gender: Male
Location: Oxfordshire
Treatment: fumaderm
#144
Sat-31-10-2015, 12:50 PM
(Sat-31-10-2015, 12:42 PM)Fred Wrote:
(Sat-31-10-2015, 12:40 PM)bassman Wrote: I cant believe it Fred

I dont get any notifications for ages, then as soon as i mention it, i get 2, in both threads you mention

Sometimes the system stops sending them if you haven't visited from the last time it sent some.

If it happens again give me a shout.  Smile


Cheers Fred
Quote
Fred Offline
I Wanted To Change the World But Got Up Far Too Late.
Moderator
Posts: 66,958
Threads: 3,888
Joined: Aug 2011
Gender: Male
Location: France
Psoriatic Arthritis Score: 1
PQOLS: 1
Treatment: Bimzelx / Coconut Oil
#145
Sat-31-10-2015, 13:05 PM
(Sat-31-10-2015, 12:50 PM)bassman Wrote: Cheers Fred

You're welcome.

Calcipotriol is a vitamin D derivative. Silkis, Dovonex and Dovobet are the most common.

Dovobet And Dovonex (What's the difference ?)
Quote
jiml Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 47,972
Threads: 357
Joined: Oct 2013
Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
#146
Sat-31-10-2015, 13:06 PM
(Sat-31-10-2015, 12:50 PM)bassman Wrote:
(Sat-31-10-2015, 12:42 PM)Bill Wrote: Good for you, Bassman. Long term use of medication often results in a squeeze between side effects and efficacy, so you are very fortunate that the maximum dosage is delivering for you. Hopefully you can reduce your dose at some stage. Out of interest, has your specialist concurrently prescribed topicals such as calcipotriol? I have found the use of accessory therapies to be very helpful in controlling the disease and allowing me to take less DMF, which is why I keep experimenting.

Cheers,

Bill

As i see it Bill, the max dosage of Fuma is more or less what it has taken to get me this far, so as far i'm concerned, i'll not reduce the dose unless i get side effect problems, which is really minimal in my case. At least its minimal in what i feel. I cannot feel what the blood tests are telling me but the doctors will tell me if there's anything untowards going on in the bloods. Like my time on  MTX, it was the bloods that said i needed to come off them. I didnt know because i didnt feel anything

If the blood test revealed anythingon Fuma, then yes i would reduce the dose, but i feel this isn't necessary at the moment.

As for Calcitropiol, i've never heard of that and has never been offered to me by any consultant

Bassman if you get to a stage where the Fumaderm is working well without side effects, it is a good idea to reduce the dose if you can without the psoriasis getting any worse.
Then if you do unfortunately have a flare in the future, you will be able to increase the dose again to push the disease back.
Working on maximum dose is ok and there's no reason not to stay on it if your blood work is good, but if you can cut back, it will give you a cushion to fall back on in the future  Thumb
Just my opinion,
By the way calcipotriol is what is in Dovonex a vitamin D derivative Dovobet And Dovonex (What's the difference ?)
Quote
jiml Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 47,972
Threads: 357
Joined: Oct 2013
Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
#147
Sat-31-10-2015, 13:07 PM
Double bubble Big Grin Fred
Quote
Fred Offline
I Wanted To Change the World But Got Up Far Too Late.
Moderator
Posts: 66,958
Threads: 3,888
Joined: Aug 2011
Gender: Male
Location: France
Psoriatic Arthritis Score: 1
PQOLS: 1
Treatment: Bimzelx / Coconut Oil
#148
Sat-31-10-2015, 13:08 PM
(Sat-31-10-2015, 13:07 PM)jiml Wrote: Double bubble  Big Grin  Fred

Five
Quote
bassman Offline Author
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 129
Threads: 3
Joined: Sep 2015
Gender: Male
Location: Oxfordshire
Treatment: fumaderm
#149
Sat-31-10-2015, 13:17 PM
Thanks for the info, so ok, yes i know what it is now.

Over the years, i've had all of those. I still have unfinished tubes of Silkis and Dovobet ointment. I also have an unfinished tube of Diprosalic though not sure if that comes under the Calcitropiol umbrella. Also have an unfinished bottle of Dovobet Gel.

None of the above have been much good in my own experience
Quote
jiml Offline
100 + Member I Just Cant Stop !

100 + Member I Just Cant Stop !
Posts: 47,972
Threads: 357
Joined: Oct 2013
Gender: Male
Location: Norwich England
Psoriasis Score: 3
Treatment: Skilarence 5x120mg a day
#150
Sat-31-10-2015, 13:23 PM (This post was last modified: Sat-31-10-2015, 13:24 PM by jiml.)
(Sat-31-10-2015, 13:17 PM)bassman Wrote: Thanks for the info, so ok, yes i know what it is now.

Over the years, i've had all of those.   I still have unfinished tubes of Silkis and Dovobet ointment. I also have an unfinished tube of Diprosalic though not sure if that comes under the Calcitropiol umbrella. Also have an unfinished bottle of Dovobet Gel.

None of the above have been much good in my own experience

Possibly not much use on their own if your skin is used to it
But to help with a stubborn spot while on Fumaderm I use a drop of Dovonex gel .... I have no idea if it works I just assume it does because the spot goes down

I'm on 4 big boy tablets a day now, and if I get a flare, I have 2 more steps back up I can use for control, I meant to add that in the last post  Confused
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