Fri-15-01-2016, 04:42 AM
Hi Caroline, I don't doubt that DMF is much safer than MTX, but there are risks with any medication. My caution with the drug is not because I think it rubbish. I think it the best treatment available, but I want to stay on it for a long time. The big dose I take currently lasts about four days, and with accessory medication I can eek this out to seven. I am due for another blood test and if this turns out well I will go back to twice weekly dosing again as this offers a superior management of my illness. As with many long term meds, the battle is often one of having to balance efficacy and toxicity at increasing doses. Phil was on the minimum dose and still had a dangerous lymphopenia.