Psoriasis in one location and years later in other places on human body?

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Does anyone notice psoriasis, and dupytren’s at ring finger and palm, and female hyperplasia? Or psoriasis started in one location, then collagen overgrowth of skin cells in another location some years later, like it spreads over several years? He’s anyone used gene therapy. Has anyone had genetic mapping to find alleles or amino acid sequences that are not normal. Gene mapping is about $700.00 in the Los Angeles, California area clinics and San Francisco clinics. Currently gene mapping is commonly used to find breast cancer such as Brac. I read up to 25%of people in Great Britain have collagen overgrowth issue in the palm of one of their hands during their lifetime.