Wed-22-12-2021, 21:20 PM
Hi yes I've read of a few studies of Multiple Sclerosis patients who take DMF for their condition, having then got covid but only mildly .
This is an excerpt I found
Source..Recovery Evaluation of Covid-19 Therapy
This is an excerpt I found
Quote:
Summary of information on dimethyl fumarate in COVID-19
DMF is thought to prevent NLRP3 inflammasome activation and the process of
pyroptosis (inflammatory cell death) through its action on the protein gasdermin D
[1]. SARS-CoV-2 induces inflammasome activation and the degree of activation is
thought to correlate with disease severity [2]. DMF has demonstrated anti-viral and
anti-inflammatory effects against SARS-CoV-2 in vitro [3]. Other inflammasome-
modulating drugs, such as colchicine, have demonstrated provisionally promising
results in small randomised trials [4, 5]. DMF is licensed to treat relapsing remitting
multiple sclerosis and plaque psoriasis as a long-term immunomodulatory agent and
is generally well-tolerated with no major safety concerns [6, 7]. The UK COVID-19
Therapeutics Advisory Panel has recommended that RECOVERY investigate the
safety and efficacy of DMF in an early phase assessment among patients
hospitalised with COVID-19
Source..Recovery Evaluation of Covid-19 Therapy