Initial study reports distinct improvement from "Ozone Sauna & Ozonated Olive Oil" in the treatment of psoriasis with minimal risk.

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Psoriasis is an immune-mediated skin disease in which genetic and environmental factors have a significant role. Olive oil with antioxidant properties is an effective adjunct treatment for skin diseases. Furthermore, ozone by introducing O2 into the bloodstream controls the response of cell-mediated immunity and leads to improve disease. So, the aim of this study was to evaluate the efficacy of ozone therapy in the treatment of Psoriasis.

Topical therapy of lesions of a man suffering from psoriasis was carried out using ozonate olive oil two times a day and ozone sauna once a week during a month. Patient showed considerable improvement after about twenty days.

As the itching and silvery-white scaling decreased, the lesions began to resolve after three weeks. Furthermore, no recurrence was noted after 3 months of follow-up.

It is suggested that ozone therapy, in appropriate formulations and in controlled cases, has a role in the treatment of patients with psoriasis by inhibiting the inflammatory pathways and prompting regenerative characteristics, without significant adverse effects and the necessity for systemic pharmacological agents. So, more studies on a greater population are needed to confirm this finding.

Source: onlinelibrary.wiley.com

*Funding: The authors had no funding

Very interesting.
I do wonder what ozone could do regarding psoriasis.
Some internetting shows that it does something with pathways and reducing IL-17, so it does make sense this treatment in the sense that it is explainable.
Now we only have to conquer the small research group.

This sounds interesting - I wonder how you have an ozone sauna, would you have to wear an oxygen mask?

(Thu-18-06-2026, 09:42 AM)Turnedlight Wrote: This sounds interesting - I wonder how you have an ozone sauna, would you have to wear an oxygen mask?

Good question, but it doesn’t' say he had a mask.

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The ozone sauna system (Gardina Company, Tehran, Iran) consisted of a cabin made of plastic laminate material, with an internal volume of approximately 440 L. Ozone-enriched oxygen (O2–O3 mixture) was generated by an ozone device equipped with a photometric O3 concentration controller and was continuously circulated through the cabin at a rate of 1 L/min. The ozone concentration was progressively increased from 15 to 25 μg/mL throughout the treatment sessions. Steam was produced by a thermostatically controlled heating element set at 90°C, maintaining the cabin temperature between 46°C and 50°C throughout the session. Each treatment session lasted approximately 20 min. At the end of each session, the gas flow was stopped and the residual gas was quickly evacuated. Subsequently, the participant was instructed to take a shower immediately. Ozone sauna therapy was performed once per week. Moreover, the participant was treated with topical ozonated oil], twice a day. Both treatments were administered concurrently over the same one-month period.