Dear PsoriasisClub friends,

This post will tell about a treatment I have followed in the past year. This is the short version, you can read the long version in my new thread in the Members Journals, called [Group Specific], which will give you an insight over the last/past year.
You can only access the Members Journals, when you are a member, and have more than ten posts, that is obvious.  

Yet Long ago I came in contact with a doctor who prescribed me Psorinovo, which is the Dutch version of  Dimethylfumarate (enteric coated, slow release), and as you perhaps found out, I am a fan of DMF and I published quite some posts on that subject. (Dimethylfumarates and Psoriasis)
The product Psorinovo has been developed by a different doctor than the one who prescribed me, and after a number of years I came into contact with this doctor.
He pointed me to a site of his in which he described the contents of a treatment called auto-vaccination.
This treatment makes it possible to treat all kinds of diseases that have to do with the immune system. The basics of the treatment is already very old, in the time when antibiotics were not yet discovered, it was a normal treatment, for everything where bacteria were involved,  but as this treatment was a very slow one and after the discovery of antibiotics which appeared to be way faster, the Auto-vaccination treatment disappeared out of sight.

This doctor now has enhanced the treatment, made it according to modern standards of medics.

Auto-vaccination is aimed at enhancing the immune system to cope with all kinds of bacterial DNA that we all have floating in our body due to bacterial infections that we all have gone through. Imagine as a specific (but not limited to this) example of being bitten by a tick(nasty animals), which also can release bad bacteria in your body. Your immune system will deal with that but residues of DNA of these bacteria will stay floating around encapsulated by a fatty layer.
When for some reason this dna reaches certain places and looses its fatty layer, it can cause trouble in a great variation as we for instance know of Lyme’s disease.

Now there is in the mean time done quite some scientific research on bacteria related to immune diseases like psoriasis. I am quite sure that Fred somewhere on the site also has a report of such a research but there are more.

So…… It might be that….IF part of the cause of Psoriasis is located in bacteria, that this treatment might help.
I have been thinking about this treatment for three whole years. Reading about it, weighing it, while in the mean time I was using DMF for a very long time.
I hope that I still have to go for a very long time in my life. I did not know how long the DMF would stay working, though I know people who are using it way longer that I do, without problems. Also on several levels DMF seems to be some magic potion, more and more research is being done and industry gets involved, for instance leading to expensive products with DMF.

Let's not divert from the subject
I have been reading the testimonies of people who have followed the Auto-vaccination treatment and finally I also have spoken personally with them.
The Auto-vaccination treatment is harmless. Your blood is being taken in 12 small tubes, which undergo a process that clears the fatty layer from the DNA. This takes a number of weeks. Then the reworked blood can be injected back into your body. The injection is normally at a location close to your lymphatic system. This will see the DNA, conclude that it is not body owned and will start removing it by creating the correct T-cells for it. In other words, you are training your T-cells on recognising this DNA and get rid of it. If in the end of the treatment the T-cells see this DNA, it recognises it and will remove it.
(A really medically educated person probably will tell this differently, but well medics is totally not my profession, I can put a band-aid on someone but that is about it).
Every two weeks, you get an injection, or you self inject.

I decided to go for it.

By now I have had two treatments of 12 injections. And I am not using any medication anymore.

As this is certainly not a common type of treatment, I did not want it to be on the forum, without at least knowing and experiencing more.

On average my P and PsA is not gone, but it lays low, sometimes comes up a little, sometimes is hardly feelable, which is quite different from when I think back to before I used MTX ( ) and DMF, when a 15 minute walk was a painful hell.
Now I still can dance, walk, cycle, etcetera, for several hours.
As I said, it is not gone, I have tiny spots of P under my hair, and certainly the PsA is not fully gone. But…. I do not use medication anymore…

If you would like to read about my adventure, look into the Members Journals for [Group Specific].

Thank you Caroline for posting this short version of your journal, I find the idea of auto vaccination fascinating and reading through it I can see you have given  it a great deal of thought and waited over a year to see the results before publishing ,

I think the results you post are without doubt fairly conclusive that the treatment is having an effect on your psoriatic arthritis. It has taken a long time to work and the working has been gradual.....but you have methodically recorded your progress in your full journal are you hopeful that the improvement will continue?

Will you need more of your blood treated in the future for the treatment to continue working  do you think ...what has been the experience of others that you spoke to that had undergone the treatment ....

It's a very interesting concept and I look forward to reading of your continued success without medication

Thank you for sharing this with our guests Caroline, I'm sure it will be of interest to a lot of people.

As you know I have read the full version, and have made my comments to you so I won't run over it all again apart from to say.

You documented the Dimethylfumarates and Psoriasis very well and it is an interesting read, and you have succeeded again with this and the full version is well worth a read.  

I will also give a small comment on this thread and say it's not something I would try. The main reason being I don't think it would be man enough to cope with the amount of psoriatic arthritis I have had, and I'm also not yet convinced that part of it's success could be down to the fact that you also played around a bit with your diet.

But hey it would be wrong of me to agree with you.

(Thu-02-02-2017, 22:30 PM)Fred Wrote: But hey it would be wrong of me to agree with you.

Wow that's really interesting! However, weren't you worried you might catch something nasty from the previously encapsulated stuff rather than managing to create the antibodies?

(Fri-03-02-2017, 00:28 AM)Turnedlight Wrote: Wow that's really interesting! However, weren't you worried you might catch something nasty from the previously encapsulated stuff rather than managing to create the antibodies?

Hi TL,

Good question.
But no, I was not afraid of that.
In those years before the treatment I have read and tried to understand as good as possible how it worked, and later in the conversations with my doctor, we also spoke about the functioning of the treatment, but it appears that 'only' the DNA can do no harm.
It are the Cell Wall Deficient Bacteria (CWDB), these are the expected micro organisms that can cause the trouble.
In the treatment these CWDB are broken down to their base components, in which are the anti-gens that are necessary to train the immune system.
Because they are broken down, they can do no harm anymore as they are no micro organisms anymore.

And what was reassuring for me was that a number of people has gone before me and had good results.

A really fascinating read, Caroline. Thank you so much for sharing. I will post here and leave your members journal unsullied.

Cheers,

Bill

Thanks for sharing Caroline. I will admit that even with your excellent explanation, I don't totally understand the process. If things became worse for you, would you repeat another round and would it be for as long or would there be a maintenance type treatment?

I wish you continued success and will follow your updates.

(Fri-03-02-2017, 13:34 PM)Kat Wrote: Thanks for sharing Caroline.  I will admit that even with your excellent explanation, I don't totally understand the process.  If things became worse for you, would you repeat another round and would it be for as long or would there be a maintenance type treatment?  

I wish you continued success and will follow your updates.  

Thanks for the compliment Kat, I must say it was not easy make an overview over a whole year, but my journal is in fact the log of all that happened.

I don't know if things will get worse, that is unpredictable as the treatment is still working, and it can take a very long time until it reaches its final endstate. I have spoken to other patients who report also slow recovery, so it still can increase and become better
If I would get worse instead, then I will talk to my doc again on what is the best way to go. I am prepared to do another round of 12.
I am also prepared to do another round, if I would reach no further progress in the coming months.

There is not something as a maintenance type of this treatment. When your immune system has learnt to deal with it, the problems should be gone or limited to the level reached.
Of course, in the rest of my life, i will pick up other bacteria, like everyone does. It may be that at a certain point it is wise to redo the treatment again. As it protects you from bacterial infections, just like an influenza injection protects for the influenza virus.

It is kind of an unsure future as there are no statistics yet. But for now I am very happy to be medication free.

This is very interesting

How many injections did you have until now? Do you notice anything?