New member here - just started on Siliq

[hithere2233]

Hi All-

Have had severe psoriasis for about 15 years.  Started around the age of 35 or so.  Tried a bunch of steroid ointments which helps minimally.  I was my derms first patient for biologics many years ago.  I believe it was Enbrel.  Can't remember I've gone through so many.  Most of them work for me for a couple of years, then start to lose their effects.  Start to see positive results in a few weeks, then about 4 months for about 80-90% clearances.

After Enbrel, started Humira, then Stelara, then Cosentyx.  Cosentyx worked for about 3 years until the beginning of this year.  Was about to start Taltz, but my derm said I could try Humira again since Taltz doesn't work too well, from his experience.  Went back on Humira for a couple of months, but didn't see any improvement this time around.

My derm suggested I try giving my body a break from the biologics.  So after a few weeks of weening myself from those, and my psoriasis flaring up like crazy...worst I've ever experienced because I've always had the various drug treatments, I started on Otezla(oral pill). 

Well, about 4 weeks into Otezla, I became severely allergic.  I mean, rashes and bumps all over my body.  The itchiest experience you can imagine.  Many, many times worse than any psoriasis itchiness I've experienced.  

I ended taking over 100mg of Claritin a day for 3 weeks.  And of course, immediately stopped taking the Otezla.  Had to rid my system of all traces, so went cold turkey without any psoriasis meds for another couple of months, so you can imagine how bad the psoriasis became.

Anyhow, started on Siliq about a month ago and the results are promising.  Truth be told, other than the Humira on the 2nd round, all the injection treatments have worked pretty well.  I just hope Siliq works as well as the others in clearing up my condition.  And, that it continues to work for years to come or until another (or better) solution is developed.

Thanks for reading and letting me share my experience.

[Kat]

Welcome!

Wow you have quite the experience with biologics!

I hope you have good luck with Siliq. I hope you'll keep us updated on how you're doing!

[Caroline]

Hi there,

Welcome to Psoriasisclub.

You have had quite a series of treatments, very unfortunate for you that they all stop working. Hope you will do well on Siliq again. Did you ever take a look at alternative treatments ? Like food, etc. ?

Cheers.
Caroline

[Turnedlight]

Hi, nice to meet you

I notice you say it was suggested to have a break from biologics - was it from a health and safety point of view or the idea they may work better after a break?

Hope you like the forum

[jiml]

Hi and a big   to the forum, here you will learn the experiences of others on various treatments without bias towards any particular treatment, here it’s all about sharing experiences and learning from each other.
I hope you enjoy the forum and what we have to offer and also I hope Siliq is the one to give you long term clearance .... it seems as if you have been through the current list of biologicals so really hope it works for you.
I don’t think the treatment I’m on is a available in the USA yet but it’s something you could look at for the future as if you could get it it could give long lasting clearance as it has for me see [post=117689] it’s a similar drug to the one I’m on which is Fumaderm and I’ve had over 6 years clear on it

Good luck and hope to hear more of your experience
Jim

A great way to keep up to date with what’s new in treatments and members experiences is to subscribe to our free monthly newsletter you can do that by clicking Groups and then click join group  

[Fred]

Hello hithere2233   to Psoriasis Club.

You story just goes to prove how difficult it is to find the right treatment, there is no one suit fits all.

I hope you get a good result from Siliq (aka Kynteum in the EU)

Don't hesitate to start another thread in [forum=10] about your treatment if you wish, it's a good way of keeping track and your information could help others.

Regards.

Fred.

[hithere2233]

Hi there,

Welcome to Psoriasisclub.

You have had quite a series of treatments, very unfortunate for you that they all stop working. Hope you will do well on Siliq again. Did you ever take a look at alternative treatments ? Like food, etc. ?

Cheers.
Caroline

Yes, I've alternated between different diets, food groups, etc.  Haven't experienced any noticeable differences.  Have not tried a lot of alternative treatments.  But those I have, didn't work for me.

[hithere2233]

Hi, nice to meet you  

I notice you say it was suggested to have a break from biologics - was it from a health and safety point of view or the idea they may work better after a break?

Hope you like the forum  

The break was because the second round of Humira had very little(5%) improvement.  I was otherwise healthy and without side effects.  So we went with Otezla, which is an oral administration(pill).  Won't be doing that again!