Health Boards
Tue-09-01-2018, 11:39 AM
Hi, I have been reading the forum as a guest for a few years now and decided it was time to try and add something to the debate. I am a 59 year old man and have have plaque and nail psoriasis for around 20 years.
I noticed there is not much history of Apremilast (Otezla) use and I have recently started on it so might be able to add something.
For what it's worth a short history of my treatments is as follows;
Various creams - not very effective.
PUVA - worked quite well and I got a home lamp made from an old sunbed which was effective but eventually the Dermatologist decided I had had enough sunlight for one lifetime.
Accitretin - made the psoriasis worse and made my lips peel! Awful stuff (for me anyway).
Ciclosporin - very effective after about 3 months use but had to come off it due to raised blood pressure.
Methotrexate - seemed to work but I only stuck it for a month as I felt run down and slightly ill all the time.
Fumaderm - I have been on and off this for around 2 years, it was very effective clearing nearly everything but my nails, but eventually had to come off due to very low blood count which wasn't recovering. I never quite got over the stomach problems with Fumaderm, never straying too far from the loo until after 11.00 am, but I felt it was worth the discomfort.
Otezla - started 3 weeks ago, no real side effects so far, felt a bit nauseous in the mornings but that's gone now. Hard to tell if it's working yet but it hasn't made it any worse!
I'll try and update on the Otezla in a few weeks time.
I noticed there is not much history of Apremilast (Otezla) use and I have recently started on it so might be able to add something.
For what it's worth a short history of my treatments is as follows;
Various creams - not very effective.
PUVA - worked quite well and I got a home lamp made from an old sunbed which was effective but eventually the Dermatologist decided I had had enough sunlight for one lifetime.
Accitretin - made the psoriasis worse and made my lips peel! Awful stuff (for me anyway).
Ciclosporin - very effective after about 3 months use but had to come off it due to raised blood pressure.
Methotrexate - seemed to work but I only stuck it for a month as I felt run down and slightly ill all the time.
Fumaderm - I have been on and off this for around 2 years, it was very effective clearing nearly everything but my nails, but eventually had to come off due to very low blood count which wasn't recovering. I never quite got over the stomach problems with Fumaderm, never straying too far from the loo until after 11.00 am, but I felt it was worth the discomfort.
Otezla - started 3 weeks ago, no real side effects so far, felt a bit nauseous in the mornings but that's gone now. Hard to tell if it's working yet but it hasn't made it any worse!
I'll try and update on the Otezla in a few weeks time.
to Psoriasis Club. 
