Risk of depression in psoriasis, psoriatic arthritis and ankylosing spondylitis

[Fred]

This study looked at the risk of depression, suicidal ideation, and suicide attempt in patients with psoriasis, psoriatic arthritis and ankylosing spondylitis patients.

Quote:

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Background:
Sparse information is available concerning mental health issues in psoriasis, psoriatic arthritis (PsA), and ankylosing spondylitis (AS) patients.

Objective:
To estimate risk of depression, suicidal ideation, and suicide attempt in patients with psoriasis, PsA, and AS, respectively, compared with the general population.

Methods:
This population-based cohort study analyzed 36,214 psoriasis patients, 5,138 PsA patients, and 1,878 AS patients who were frequency-matched with a general population cohort. Annual incidence rate of depression, suicidal ideation, and suicide attempt was calculated separately for psoriasis, PsA and AS.

Results:
There was an increased risk of depression in the three cohorts; adjusted IRR: psoriasis, 1.14 (95% CI, 1.11, 1.17); PsA, 1.22 (95% CI, 1.16, 1.29); AS, 1.34 (95% CI, 1.23, 1.47). There was no significantly increased risk for suicidal ideations or suicide attempt among psoriasis, PsA, or AS patients.

Limitations:
Patients were not excluded if previously diagnosed with depression, suicidal ideation, or suicide attempt. Suicide attempt and completed suicide analyses were not adjusted for presence of depression. Use of systemic psoriasis treatment to measure severe psoriasis could lead to psoriasis severity misclassification.

Conclusion:
The risk of depression, but not suicidal ideation or suicide attempt, was significantly increased in patients with psoriasis, PsA, and AS.

Source: onlinelibrary.wiley.com

*Early view funding unknown.

[pingu]

I don't think a study was needed to highlight an increase in depression among psoriasis sufferers. However I think it is a large step from depression to suicidal tendencies. However I would anticipate some increase and correlation there.

Also there is a significant difference between depression and "my psoriasis is getting me down today" which is where I was at when I sought my referral 18 months ago.

I hope anyone who does suffer depression to a clinical level receives the help and support they need and indeed simply talking here may help and I know many members are happy to even talk to people if it may help.

Don't suffer in silence, reach out and find a friendly ear first. More help is available.

[Fred]

I hope anyone who does suffer depression to a clinical level receives the help and support they need and indeed simply talking here may help and I know many members are happy to even talk to people if it may help.

Don't suffer in silence, reach out and find a friendly ear first. More help is available.

Yes we have many members willing to listen and help if they can, and we have a dedicated thread in the members only boards: [Group Specific]