Bone mineral density and VitD3 in patients with psoriasis and/or psoriatic arthritis

[Fred]

This study ahead of publication looked into correlations between vitamin D status and bone mineral density (BMD) in patients with psoriasis and/or psoriatic arthritis.

Quote:

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Limited data are available on the vitamin D3 status and bone mineral density (BMD) of patients with psoriasis or with psoriatic arthritis.

Our study intended to explore possible correlations between vitamin D status and BMD, as well as among these parameters and the features of the underlying disorder.

Seventy-two patients with psoriasis/or psoriatic arthritis (female : male ratio, 40:32; mean age, 58.5 ± 11.6 years; mean duration of follow up, 142.7 ± 147.7 months) participated in the study. We evaluated the characteristic clinical features of the underlying disease, performed bone densitometry of the lumbar spine and the hip region, measured the serum vitamin 25(OH)D3 levels of the patients, and undertook the statistical analysis of the relationships between the clinical and the laboratory parameters.

The proportion of patients with a low BMD value did not exceed that seen in the general population. We found an inverse correlation between the serum level of vitamin 25(OH)D3 and body mass index, as well as between the former and the severity of skin involvement. Furthermore, the activity of psoriatic arthritis was significantly higher in patients with inadequate vitamin D3 status. In patients with psoriatic arthritis, BMD significantly exceeded the values measured in patients suffering from psoriatic skin lesions only.

Our findings suggest the importance of evaluating the vitamin D3 status and screening for comorbid conditions in patients with psoriasis or psoriatic arthritis. This appears justified, in particular, due to the possible role of hypovitaminosis D3 in provoking the development of skin lesions and joint symptoms.

Source: onlinelibrary.wiley.com

*This is an early view before publication.
Funded by: Hungarian Research Grants.

[jiml]

So basically it's saying don't overdose on vitamin d3 supplements it can cause more damage than good. If I'm reading it right

[Fred]

So basically it's saying don't overdose on vitamin d3 supplements it can cause more damage than good. If I'm reading it right

I don't think it's suggesting supplements are the problem, but it's an early publication so we may know more later.  

[jiml]

So basically it's saying don't overdose on vitamin d3 supplements it can cause more damage than good. If I'm reading it right

I don't think it's suggesting supplements are the problem, but it's an early publication so we may know more later.  

It may not be suggesting that but it points that way Hypovitaminosis D3 is overdosing of vitamin D3

[Turnedlight]

I'm probably being daft, but I'm reading it as follows - the inverse correlation is that the higher the levels of d3, the lower the bmi, also, the higher the levels of d3, the lower the severity of skin probs.

And I assume 'hypo' means not enough, hyper means too much.. So hypovitaminosis is a deficiency, not an overdose.

Makes a very interesting article, since I have never once been tested for vit d levels or had it suggested to me to start taking any. I have recently started, just to see if it makes a difference..

[jiml]

I'm probably being daft, but I'm reading it as follows - the inverse correlation is that the higher the levels of d3, the lower the bmi, also, the higher the levels of d3, the lower the severity of skin probs.

And I assume 'hypo' means not enough, hyper means too much.. So hypovitaminosis is a deficiency, not an overdose.

Makes a very interesting article, since I have never once been tested for vit d levels or had it suggested to me to start taking any. I have recently started, just to see if it makes a difference..

You are not being daft on this occasion that's me misreading the article. Thanks for enlightening me
You are quite right I have read it wrongly I read it as hyper not hypo
It is a deficiency of vitamin D3 , not an overdose as I previously wrote, I have never had my vitamin levels checked either
I had better edit my earlier post

[Turnedlight]

Funny that, it would be a pretty simple thing for the doc to do. I might try and persuade them to add a vit d3 test to my next blood test.

[jiml]

Funny that, it would be a pretty simple thing for the doc to do. I might try and persuade them to add a vit d3 test to my next blood test.

Yes it might be a good thing to know, I assume they can add that to the list of things to test for

[Kat]

My doc checks my levels every 6 months and has for about 5 years now, before I was diagnosed with psoriasis. I've always been deficient.

[Turnedlight]

Do you take d3 supplements?