Correlation between psoriasis and dupuytren contracture

[Fred]

Dupuytren contracture (DC) is a fibrocontractile disease of the palms where the fingers bend towards the palm and cannot be fully extended, this study looked at the correlation between psoriasis and dupuytren contracture.

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Aim:
To evaluate the prevalence of DC in the full range of clinical psoriasis phenotypes.

Methods:
In total, 98 patients with psoriasis attending our psoriasis clinic were examined for DC, based on predetermined criteria. In addition, 84 patients with DC, obtained from a specialist hand clinic, were assessed using a validated psoriasis questionnaire. We utilized Bayes theorem and bootstrap simulation to calculate the conditional prevalence of DC, then we used the results to compare the prevalence of DC between patients with psoriasis and a nonpsoriasis population.

Results:
The percentage of patients with DC was 19.6% in the psoriasis population and 3.6% in the nonpsoriasis population. Development of DC showed a phenotypic predilection, with 39.1% of patients with predominantly palmoplantar involvement and 38.9% of patients with intertriginous psoriasis developing DC compared with 12.7% of patients with psoriasis who did not have these two phenotypical presentations.

Conclusions:
Our data show a positive correlation between psoriasis and DC. Patients with the palmoplantar phenotype of psoriasis were more likely to develop DC. By understanding this relationship, dermatologists may diagnose DC early in its onset in patients with psoriasis, prompting referral to hand surgeons when appropriate.

Source: onlinelibrary.wiley.com

[Quest4Cure]

Thankx Fred   for adding all the info on DC.

I have it badly in my right hand . With PsA. And Palmoplanter PPP.
It's like science went wako on My hands and feet . One thing leads to another.i already have been thru 3 hip replacements and fighting not to have knees. Havana screws in my shoulders. Alll from PsA.

I think that every time I try to fix my fingers with extra collagen build up thru the same pathway psoriasis build up.
P is found to cause skin conditions. Dupuytrens had curled my hands with a build up of collagen pulling my fingers into a fist. After surgery on one pinky finger all fingers flared and are curled and disfigured.  Tried NA. AND BIO DRUG XIAFLEX.,EACH TIME MY DC GET'S A WORSE FLARE.
Next radiation therapy.. Stopping the nodules and thickened tendons from a collagen build up is the goal.

So I have heard of the Keobler Effect. Patients who develop Koebner phenomenon in response to one method of injury are susceptible to other triggering stimuli. This is particularly noted in patients with psoriasis. Conversely, a patient who does not develop skin lesions with one type of injury is not expected to exhibit Koebner phenomenon with another type of injury.i seem to be one of the luck ones, one flare after another.

I don't hear many talking about Dupuytrens or thevKeobner phenomenon. I feel like I'm running around in circles at times.
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