Thu-14-07-2016, 13:41 PM
Long-term Safety of MTX
The profile of side effects of MTX has been studied over 25 years, with very few clinically important adverse effects in the weekly low doses used for RA/PsA/P therapy. Indeed, MTX courses show some of the longest continuation rates reported in clinical medicine, obviously as a result of both its efficacy and safety. The safety profile of MTX indicates that it is among the safest of all drugs used for the treatment of chronic inflammatory arthritis.
I still think that MTX has it's place and is not as bad as it's made out, people are very prejudice against it and even though it has some side effects when you look at some of the other treatments available it is, on balance, no worse than others. It is used quite a lot more than many other treatments so really I think that it is difficult to evaluate constructively,I used it for 9 years with increasingly bad side effects but it did work especially for the PsA , the side effects for the Cyclosporine were far worse than MTX . The long term effects for a lot of the new treatments are not known as they have not been out long enough to do the same in depth of research that MTX has had .
The profile of side effects of MTX has been studied over 25 years, with very few clinically important adverse effects in the weekly low doses used for RA/PsA/P therapy. Indeed, MTX courses show some of the longest continuation rates reported in clinical medicine, obviously as a result of both its efficacy and safety. The safety profile of MTX indicates that it is among the safest of all drugs used for the treatment of chronic inflammatory arthritis.
I still think that MTX has it's place and is not as bad as it's made out, people are very prejudice against it and even though it has some side effects when you look at some of the other treatments available it is, on balance, no worse than others. It is used quite a lot more than many other treatments so really I think that it is difficult to evaluate constructively,I used it for 9 years with increasingly bad side effects but it did work especially for the PsA , the side effects for the Cyclosporine were far worse than MTX . The long term effects for a lot of the new treatments are not known as they have not been out long enough to do the same in depth of research that MTX has had .