Thu-26-09-2013, 18:28 PM
The number one reason that biologics fail is not because of side effects; its because patients do not receive significant improvement in a short period of time. For psoriasis, adding 25 mg of MTX will more likely bring more immediate response. The goal then would be to tapper off. It's also worth noting that biologics do not have the best track record for the higher order psoriasis conditions. The biologic maybe uses for PsA and the MTX maybe used for PP.