Stelara round two

[Caroline]

It is a rotten disease and you have my sympathies. I was reading about hematopoietic stem cell transplantation (not with regard to psoriasis) and realised it was the possible permanent cure that Caroline was talking about, although I am a little skeptical about its efficacy. What did interest me was the idea that auto-immune disease can result from specific leukocyte clones which tend to displace other lineages. HSCT attempts to restore variation to the immune system, although it is a little less successful at this with one type of T cell. The disease model fits for psoriasis, where it is easy to imagine a plaque causing lineage of T lymphocytes becoming dominant and wreaking havoc. Maybe DMF works by creating a better balance of leukocytes?

Anyway, good luck with your treatment. I think I can definitely add curries to the list of no-go foods for DMF. No headache thankfully, but a kick in the guts I could have done without.

Cheers,

Bill

Bill, we are hijacking Fred's Stelara thread. I have an answer to you over here in post RE: Bill's pure dimethylfumarate thread