Bill's pure dimethylfumarate thread

[Caroline]

It is a rotten disease and you have my sympathies. I was reading about hematopoietic stem cell transplantation (not with regard to psoriasis) and realised it was the possible permanent cure that Caroline was talking about, although I am a little skeptical about its efficacy. What did interest me was the idea that auto-immune disease can result from specific leukocyte clones which tend to displace other lineages. HSCT attempts to restore variation to the immune system, although it is a little less successful at this with one type of T cell. The disease model fits for psoriasis, where it is easy to imagine a plaque causing lineage of T lymphocytes becoming dominant and wreaking havoc. Maybe DMF works by creating a better balance of leukocytes?

Anyway, good luck with your treatment. I think I can definitely add curries to the list of no-go foods for DMF. No headache thankfully, but a kick in the guts I could have done without.

Cheers,

Bill

Hi Bill,

This is a split from the Stelara thread post RE: Stelara round two as we were stealing Fred's thread.

I think what you are suggesting is very interesting and maybe it is indeed the treatment I am pointing to, or better said referring to. I am not sure though. Stem cell transplantation is very complex. The treatment I am referring to is an already very old technique that slipped into oblivion because of the fact that much easier medication came available for several immune approaches like the histamines, antibiotics, etc, that work immediately while the old treatment will take you at least a year.

The technique is described by Barger J A, Horgan E en Horgan J  in 1929 in the ‘Journal of American Medical Association’ called auto vaccination.

The site where I got this from is the site of the same doctor that developed Psorinovo. Unfortunately for you the whole site is in Dutch. You can get the link from me, but translating this complete site is quite a bit too much. The descriptions are extensive.
I can deliver a reading list of articles that are in English if you can find them anyway on the Internet.

Another approach has a.o. to do with the diversity of the intestine bacteria. That is where FMT Faecestransplantation is pointing at, think of Crohn's disease.

Caroline