Wed-17-06-2015, 21:57 PM
(Wed-17-06-2015, 21:39 PM)Caroline Wrote: It will not kill you Fred, but it is quite dangerous.
If you search on google for "methotrexate and PML", you get quite some hits on this combination. Like NO LINKS ALLOWED. It's not the methotrexate that causes the dangerous PML, but it are the effects of the methotrexate that are dangerous,
Just like one has to stop with DMF if your lympho count get too low.
So if you go on MTX, please do keep a very good eye on your blood situation.
Caroline I don't need to search Google for methotrexate and/or anything, I have my own opinion and know it well enough. But as you know we can all find negatives about other treatments and PML, and what we have to remember is that not all treatments are available to all people.
We may not like a certain type of treatment, but we have to keep in mind of what is available to others in their situation or country they reside in.
Luckily these days they do monitor people on methotrexate in the UK unlike they did with me many years ago, and I'm just suggesting in answer to karaokeking's question on what will probably happen. I may be wrong and that is why I pointed out that none of us are medically trained, we are just people giving opinions. Yours and mine are the same (don't go for methotrexate) but in his situation I can't see another door that will be opened. However once he fails or can not tolerate it then more doors will open Hint Hint Hint.
Oh and I'm not Dutch, but probably as direct as you. (Or it has been said sometimes more direct than you)