Methotrexate Injection

[D Foster]

A study investigating folate levels in methotrexate patients with rheumatoid arthritis concluded that there is a close relationship between folate status and side-effects during methotrexate therapy and that only a minority of side-effects are reported when concomitantly measured Red Cell Folate levels are above 600 – 800 nmol/l

Raised levels of homocysteine are associated with coronary heart disease and stroke . Homocysteine levels are frequently elevated in rheumatoid arthritis patients and low dose methotrexate treatment may increase them further . Folic acid supplementation lowers the prevalence of chronic hyperhomocysteinemia .

A little bit more info Fred.