biologics or meds

[glenda grant]

[quote='glenda grant' pid='35605' dateline='1420501456']
Someone told me Enbrel is made from protein from the ovaries of a Chinese hamster.No matter what we buy seems to be made in China.Can't we use made in America?

I don't think it's actually made in China, but here you go a little bit of reading for you:

Quote:

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Etanercept is a human tumour necrosis factor receptor p75 Fc fusion protein produced by recombinant DNA technology in a Chinese hamster ovary (CHO) mammalian expression system. Etanercept is a dimer of a chimeric protein genetically engineered by fusing the extracellular ligand binding domain of human tumour necrosis factor receptor-2 (TNFR2/p75) to the Fc domain of human IgG1. This Fc component contains the hinge, CH2 and CH3 regions, but not the CH1 region of IgG1. Etanercept contains 934 amino acids and has an apparent molecular weight of approximately 150 kilodaltons. The specific activity of etanercept is 1.7 x 106 units/mg.

List of excipients:
Sucrose
Sodium chloride
L-Arginine hydrochloride
Sodium phosphate monobasic dihydrate
Sodium phosphate dibasic dihydrate
Water for injections

Thanks Fred I appreciate the information about Enbrel.I was speaking in terms of why a Chinese hamster whats the difference between American and Chinese.I guess I am just running my mouth.I am so fed up with Made in China.I try and buy made in the USA to keep our people in America have jobs.
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