Mon-18-06-2012, 09:56 AM
I took my first dose of 10mg on Friday last week... While it's too early to be seeing a marked improvement in my skin I have woken up this morning with a reduction in the inflammation, stiffness and joint pain in my hands and wrists.
So far I have had no side effects, I actually feel more energetic than I have in around a year. I'm hoping this continues, I know of people who had side effects within a couple of days of taking their first dose and who get floored for a day or so after taking it but also know of others who have experienced their first side effects after a few months of taking this medication.
On a scientific note, the dosage of MTX prescribed for psoriasis is way lower than that for cancer and as such only lowers the synthesis of folic acid derivatives slightly, it does not prevent cell replication fully or give you such a lowered immune system that you are at a very high risk of infection.. I discovered to my joy that being on the dosages of MTX for my PsA and Pso will not prevent me from working in a medical microbiology laboratory if I follow the standard rules and regulations regarding personal protective equipment.
Also, the fact that MTX has been used for over 50 years on psoriasis patients means there is a wealth of scientific and medical data out there regarding efficacy and failure rates/side effects... I'm more comfortable using this than a newer drug (or trial drug, sorry Fred) because there is less data out there.
Krissie
So far I have had no side effects, I actually feel more energetic than I have in around a year. I'm hoping this continues, I know of people who had side effects within a couple of days of taking their first dose and who get floored for a day or so after taking it but also know of others who have experienced their first side effects after a few months of taking this medication.
On a scientific note, the dosage of MTX prescribed for psoriasis is way lower than that for cancer and as such only lowers the synthesis of folic acid derivatives slightly, it does not prevent cell replication fully or give you such a lowered immune system that you are at a very high risk of infection.. I discovered to my joy that being on the dosages of MTX for my PsA and Pso will not prevent me from working in a medical microbiology laboratory if I follow the standard rules and regulations regarding personal protective equipment.
Also, the fact that MTX has been used for over 50 years on psoriasis patients means there is a wealth of scientific and medical data out there regarding efficacy and failure rates/side effects... I'm more comfortable using this than a newer drug (or trial drug, sorry Fred) because there is less data out there.
Krissie