Tremfya for psoriatic arthritis Fred's journey

[Caroline]

Has anyone tried going back to something that failed previously?  I.e. if you went back to stelara for example....maybe it would work again since you were on other types of biologics after?

Hope that makes sense 

Well KatT, the problem is that when a biological is failing, that is mostly due to the fact that your body is making anti-bodies against the medication. Just like when you would get Covid-19, then the body makes anti-bodies and will deal with the Covid. Then a next time you get infected, that has no effect, as the anti-bodies immediately will do their job and kill the virus.
The same is in fact happening with the biological.
Also after some time the body will remember it and if reused, it will immediately get rid of it .

So it is not very likely that a once used bio, will start working again after a number of years.