Tremfya improved fatigue in patients with psoriatic arthritis

[Caroline]

Yes I feel better after the fogginess goes away....but I take the painkillers only once in a while..... once or twice a month on average (was trying to save what I had left from two years ago).  I did get a prescription for the same really good ones a few weeks ago so now I have tons (too much) but I have a tendency to endure aaaaand I don't want to get addicted aaaand I want to wake up in the morning.

I have a high tolerance to pain....except when I am exhausted. 
  
But my sleeping or lack of has gotten worse as the PSA progressed.  And if for example I  have a sleepless night (happens frequently), the pain is so much worse the next day.  

All this to say I linked it mostly to the pain caused by inflammation.....basically when there is pain due to PSA, there's inflammation, your body is fighting all the time, you're in pain and lack sleep thus you are more tired and get exhausted.

I think if the conclusion of this study would be the same for other biologics.

I totally agree that it's not a skin disease.  It's an auto immune disease that causes arthritis and psoriasis and other ailments (not sure this is the correct term).

Hope you sleep well 

PS.  Tell the hamster to stop spinning the wheel.  You might sleep better 

Later than I expected, this answer, had a busy day with the family, but you are still awake.
Yes, I understand that the pain is caused by the inflammation and I recognise that, only with me it is less and up to now under control.
I get your statement that tiredness can be the result of lack of sleep. And I do believe that for many people that is so.
That would indeed also imply that, no matter what medication you use, if a medication works, the pain will reduce, your sleep will get better and you will be less tired. Certainly logical so must be true.

But I also think that there is a certain part of the PSA sufferers, who have a more fundamental form of tiredness, called fatigue, which is not the result of lack of sleep, but is another side effect of our disease. So the cause of our psoriasis or PSA is also the cause of a phenomenon called fatigue.

You state that you agree that it is no skin disease.   So on there we are on the same level.
Then you say that it is an auto immune disease........   Here I begin to hesitate.
You know why?

Well “The” essential aspect of auto immune diseases, you see this with all of them, Rheum, MS, you name them, is that you can find anti-bodies belonging to those diseases in the blood. That is used as a proof that you indeed have that specific disease.
And now it appears that..... you cannot find anti-bodies in the blood of us Psoriasis or PSA sufferers. This is also seen with the diagnosis of PSA, that is extremely difficult as you cannot find anything in the blood.
So.... I am very much hesitating myself to call it an auto immune disease.
But it is a disease that is somewhere hidden in our system.

I have an idea of what it is caused by, handed to me by a doctor over here, who has studied it and treated a few thousand sufferers.

Cheers and I hope you sleep well tonight..

.....
And again I don’t really get your remark about the hamster. hihi... that is probably my lack of understanding very subtle English proverbs...