Quote:
Each of the factors, body weight (BW) over 80 kg, body mass index (BMI) over 25, or smoking habit over 20 cigarettes/day showed a higher proportion of insufficient-responders compared with responders, although the difference was not statistically significant. Patients with previous exposure to biologics showed a significantly lower response to the treatment. Furthermore, a statistical difference was identified between patients with none of these factors and patients with some of these factors.
If I read it carefully that in above sentence there is a major discrepancy.
It says in the first part that each of the factors showed a difference. But that difference was not statistically significant.
As statistics is already a very wonky type of mathematics, the conclusion of it being not significant is sufficient to admit that there is NO connection.
Then in the same sentence they say. A statistical difference was identified between the ones with none of the factors and with some of the factors.
That is contradictory.
First there is no connection then suddenly it appears to have a connection. So 0 + 0 = 1
And that all around a score of 74%, not 73%, not 75%, no.... 74.
Still I can imagine there is a difference between people who have overweight, drink, smoke and feed the cat, compared to those who don't. But I bet there is the same statistical difference between people who do not have psoriasis.
One investigation down the drain....