Bill's pure dimethylfumarate thread

[Bill]

There is much research about the role of free radicals and disease, Caroline, and I guess you know about DMFs mitochondrial effects and its proposed use in treating Friedreich's ataxia. It is a very active drug and I think it will be a while yet before its pharmacology is well understood. I have been reading a little and wonder whether most of the lymphocyte apotosis is occurring in the gastrointestinal tract. If this is the case then it would make sense to believe that nac could protect the lymphocytes from dmf induced apotosis by increasing gsh levels. There are research papers demonstrating that nac can protect lymphocytes in the gut from oxidative stress. I will have a read of some old posts.

Cheers