Bill's pure dimethylfumarate thread

[Caroline]

Well ... I think it is a balance in your body.

We always say that Psoriasis is an autoimmune disease, but.... one of our doctors here in NL, with 30 years of expertise and now retired, says: it is a mitochondrial disease.
Because of a problem in the citric acid cycle, there is a flaw in the burning of the fuel in the mitochondria. Which leads to anaerobic waste which causes the Psoriasis and Psoriatic Arthritis problem. This may be the real cause.
Still there may be genetic aspects, but they are not the cause, they influence the chance of getting it.

The problem in the cycle is where fumarates are involved. This is the reason why adding DMF leads to a better burning in the cycle and the Psoriasis and psa disappears (P and PSA are the same disease, PSA is NO comorbidity).
Of course it is only necessary to add DMF until the cycle is fully functional again. Excess DMF is not necessary and I suspect that this leads to the lowering of the lymphocytes.
So it is finding the balance that is the trick.

If above is correct, and I don’t see why not, then all treatments apart from DMF are only suppressing treatments.