Thu-14-03-2019, 18:15 PM
(Wed-13-03-2019, 22:55 PM)PKat Wrote:(Wed-13-03-2019, 21:54 PM)Fred Wrote: Interesting and Kat could be right, but looking at this Cosentyx (secukinumab) (which I made from the official guidance) it says:
Quote:
The recommended starting dose of Cosentyx for adult patients is 300 mg at weeks 0, 1, 2, 3, and 4. After the starting dose, the recommended maintenance dose of Cosentyx for adult patients with psoriatic arthritis is 300 mg every 4 weeks. (Some patients may be on 150 mg maintenance dose)
The way I read it is that 300 would be the starting dose for all, but the maintenance could be reduced to 150 if it is only for treating psoriasis. So my thinking is that you should be on 300mg and not 150 mg to get you going.
I know the nurse told me I'd be doing 2 shots so by that I'm assuming they'll start me on the 300 mg. But I had to go back and read what was on the site to make sure I didn't say it wrong and found a bit more info on what the Cosentyx site says
Edits in red which are my thoughts on it.
From their website under prescribing information:
Plaque Psoriasis • Recommended dosage is 300 mg by subcutaneous injection at Weeks 0, 1, 2, 3, and 4 followed by 300 mg every 4 weeks. For some patients, a dose of 150 mg may be acceptable. (2.1) [This goes with what Fred says as I think it reads that the 150 mg would be acceptable as a maintenance dose although it's not really clear on if it means the loading dosage as well]
Psoriatic Arthritis • For psoriatic arthritis patients with coexistent moderate to severe plaque psoriasis, use the dosage and administration for plaque psoriasis. (2.1) • For other psoriatic arthritis patients administer with or without a loading dosage. The recommended dosage: o With a loading dosage is 150 mg at weeks 0, 1, 2, 3, and 4 and every 4 weeks thereafter o Without a loading dosage is 150 mg every 4 weeks o If a patient continues to have active psoriatic arthritis, consider a dosage of 300 mg. (2.2)
[Interesting]
Ankylosing Spondylitis • Administer with or without a loading dosage. The recommended dosage: o With a loading dosage is 150 mg at weeks 0, 1, 2, 3, and 4 and every 4 weeks thereafter o Without a loading dosage is 150 mg every 4 weeks (2.3) [This is for a condition for spinal arthritis, had to look it up]
Thanks for this info Fred. I’ll definitely talk to my Rhematologist on the 20th to see her thoughts on starting me out on the 150 mg.