Dermatologist to see me Weds., said I need biologic treaetment

[Caroline]

There are many biological drugs to take, but typically the first ones to try are tnfs. There are two different ways they are administered - either through injection or an infusion. They typically start off with Remicade (infusion), however since your diabetic an infusion may not be the best choice. The stuff they mix with the drug to give you the infusion will temporarily raise your blood sugar. If they decide with a tnf, I would suggest Humira.

If you have a choice of medication, I would suggest Stelara. This drug is different than tnfs and works faster than tnfs and has less chance of failing.

I can go along with Mati. Good suggestions. Over here at the board we have a bit the impression that TNF's (which are proteins), which are biologicals that block a messenger pathway in your immune system, do have the tendency to fail in a certain time as you will be building up anti-bodies against them. Eternacept (Enbrel) would in that sense be a good one as you will not build up anti-bodies with that.
As for the Stelara, that is another type of biological, it connects and blocks interaction mainly to receptors on your cells, in the case of Stelara that is (IL-23) an interleukin that seems to have much to do with Psoriasis. We have very good experiences with Stelara here at the board.
Most biologicals are types of monoclonal anti bodies.

Question: did your ancestors also have Psoriasis? If so then at least you may have a hunch that it has a genetic cause.