Bill's pure dimethylfumarate thread

[Bill]

This is why I like you guys. Collectively we would have over a century of psoriasis experience (a bit over half of Steve Smith's first innings in Perth), yet none of us has a firm view of what I should do. Yes, DMF can cause allergies. Like any drug the body can compensate and reduce the efficacy for DMF; I had this happen at a dose of 3*240mg a day, but not at 800mg twice a week. DMF would have to be at least 25 times bigger to be at risk of my body making antibodies against it.

My disease is currently very well controlled. I have been experimenting unsuccessfully for nearly 12 months with all sorts of things to get my lymphocyte count back to normal. I have taken breaks from treatment for up to six weeks without major incident. I have noted that with my disease controlled there is less chance that a break from treatment will be problematic. With my current lymphocyte count I could be back to a normal range with a break of as little as three weeks. With a normal lymphocyte count I have been able to have a higher DMF dosage which better manages my disease. I have an opportunity to take a break now that I will not have if I wait to see if my current supplements are helping. I think a break is probably worth trying.