Bill's pure dimethylfumarate thread

[jiml]

The DMF is completely metabolised within a day I think, Fred. I have taken breaks before and have noticed slower relapses with each one, so I now think of a break as a test of my disease. The worsening of psa is my stimulus to dose again. The advantage of taking a break is that it can quickly raise my lymphocyte count: The lymphopaenia a year ago could have been resolved with a break of about five weeks. I am still of the opinion that a higher lymphocyte count will resist more frequent dosing.

You could be right about a break giving the lymphocytes time to recover, but while they are only just outside normal and reasonably stable, I don’t see the need for a break

Personally I wouldn’t take a break for fear of a big flare that might be difficult to resolve. I’m nervous about tinkering with what isn’t broken