Tremfya improved psoriatic arthritis [study]

[Fred]

I don’t understand this report.

I don't understand many of them, but I'll give my interpretation of how I see it.

They are talking abound psosriatic Arthritis, and de the scores give..... complete skin clearance... ??????
PsA and skin??

If you remove the PASI scores you will see:

ACR: The ACR (American College of Rheumatology) Criteria is a standard criteria to measure the effectiveness of various arthritis medications or treatments in clinical trials for Rheumatoid Arthritis.

HAQ-DI: The Health assessment questionnaire disability index (HAQ-DI) is a questionnaire for the assessment of Rheumatoid Arthritis.

Those are the scores of importance, but they are listing all as it's a psoriasis treatment. They're are just showing all figures relevant to the use of Tremfya.

The AE's seem ok.

But... they pronounce that they have introduced a great medication for plague Psoriasis....... and they were talking about PsA. ???

They are talking about both. Tremfya has recently got the go ahead by the FDA for psoriasis, so they are pleased to see that along side psoriasis it is doing well with psoriatic arthritis. This will bode well on seeking acceptance for psoriatic arthritis when they file for it.

And they say that one third of people with plague Psoriasis, will get PsA... is this true? I have always thought that only 10% of people with Psoriasis would get PsA.

It depends on where you read the stats. In our page Psoriasis we say it is 20%. If you look at a well known arthritis site you will find they say it is 30%

We also know that IL-23 is a typical Psoriasis messenger and IL-17 is the PsA messenger. At least that is why Cosentyx works so well.

Errrrrrrrrrrrrrrrrrm yes.