Bill's pure dimethylfumarate thread

[Caroline]

DMF is very active biochemically, and the reactivity with cysteine residues seems to be important. Because of this activity it is hard to see how it could work as a systemic anti-fungal i.e. Where is all the free DMF to do the job? The significance of fumaric acid is that DMF is readily metabolised after it has had its pharmacological effect. Dr Schweckendiek's ideas of how fumaric esters worked against psoriasis were wrong. What matters is that he tested his ideas and demonstrated a therapeutic effect.

Cheers,

Bill

Bill,

I've split this off from the diet thread of Alan. As that should not become a DMF thread.

What did you have in mind when you said: "Dr Schweckendiek's ideas of how fumaric esters worked against psoriasis were wrong.". ?

Cheers,
Caroline